{"id":"W3098274267","doi":"10.1101/773283","title":"ipaA triggers vinculin oligomerization to strengthen cell adhesion during <i>Shigella</i> invasion","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"Centre National de la Recherche Scientifique; Knut och Alice Wallenbergs Stiftelse; National Science Foundation; Consejo Nacional de Ciencia y Tecnología; Institut National de la Santé et de la Recherche Médicale; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Vinculin; Cell adhesion; Cell biology; Focal adhesion; Chemistry; Effector; Adhesion; Biology; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009197635,0.0002004663,0.0001570566,0.0001036649,0.0001386915,0.0002713455,0.0001284252,0.0001845442,0.00137721],"category_scores_gemma":[0.00007758085,0.0001116437,0.00021215,0.0000534642,0.0001325205,0.0001334582,0.00021843,0.0004545331,0.0003310725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002810023,"about_ca_system_score_gemma":0.000107106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004240747,"about_ca_topic_score_gemma":0.0005307617,"domain_scores_codex":[0.999903,0.0000112402,0.000005891934,0.00001942604,0.00002055281,0.00004001734],"domain_scores_gemma":[0.9999225,0.00001231566,0.00002062773,0.000009204142,0.000009544542,0.00002578961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003645191,0.000007910172,0.0001823361,0.00001003006,0.000001957994,0.00001903399,0.000005594066,0.00002230047,0.9995111,0.00002472762,0.00001809799,0.0001604519],"study_design_scores_gemma":[0.000007135095,0.0001152348,0.01039768,0.000004723995,0.000006270966,0.0001359975,0.00003143321,0.001105707,0.9872983,0.00002983909,0.0008639425,0.000003734885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979067,0.0002145415,0.0008656727,0.00003314058,0.000006330156,0.00000779008,0.00009036914,0.00004086122,0.0008345704],"genre_scores_gemma":[0.9986899,0.00006287015,0.0004874992,0.00003430679,0.000002971494,0.000009688965,0.0001260213,0.000009337276,0.0005773613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00137721,"threshold_uncertainty_score":0.004607201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01023121189422527,"score_gpt":0.2061225491408813,"score_spread":0.1958913372466561,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}