{"id":"W3098350592","doi":"10.1186/s13578-020-00496-y","title":"Enhancing the antibacterial activities of sow milk via site-specific knock-in of a lactoferrin gene in pigs using CRISPR/Cas9 technology","year":2020,"lang":"en","type":"letter","venue":"Cell & Bioscience","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Agriculture","funders":"National Transgenic Science and Technology Program; National Swine Industry Technology System; Fundamental Research Funds for the Central Universities","keywords":"Lactoferrin; Colostrum; Biology; Casein; CRISPR; Lactation; Genetically modified organism; Gene; Food science; Immunology; Genetics; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001656726,0.0002670748,0.0003939444,0.0002496738,0.00004162285,0.000018846,0.0005733967,0.0004666119,0.00001236999],"category_scores_gemma":[0.00004058123,0.0002376185,0.0001016788,0.000479439,0.0003625224,0.000005300138,0.0002987456,0.0004940022,0.000001244673],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003060895,"about_ca_system_score_gemma":0.0001277906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007995158,"about_ca_topic_score_gemma":0.0001183045,"domain_scores_codex":[0.9983416,0.00005688094,0.0004463527,0.0005575378,0.0001907765,0.000406865],"domain_scores_gemma":[0.9992065,0.00003304607,0.0002071278,0.0004867471,0.00003887703,0.00002763884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001801113,0.00002316734,0.0004895108,0.0001394751,0.000004121094,0.00002713008,0.0001959675,0.0002022424,0.9977017,4.060536e-7,0.001065988,0.0001322769],"study_design_scores_gemma":[0.0002189577,0.0001129142,0.0003297076,0.00007990542,0.000009723049,0.00001325309,0.00009009074,0.0002572158,0.9867182,0.00001175054,0.01192356,0.0002346629],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986326,0.00142225,0.007685685,0.003769566,0.0004407089,0.0002473053,0.0000479921,0.000009105863,0.00005138029],"genre_scores_gemma":[0.9949871,0.0003704803,0.001814266,0.002320521,0.0003821763,0.000007817807,0.00003439802,0.00003078274,0.00005249507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01098344,"threshold_uncertainty_score":0.9689802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01088258537585482,"score_gpt":0.2579619568912109,"score_spread":0.2470793715153561,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}