{"id":"W3098558150","doi":"10.1021/acs.biochem.0c00839","title":"Chemoenzymatic Synthesis of Chito-oligosaccharides with Alternating <i>N</i>-<scp>d</scp>-Acetylglucosamine and <scp>d</scp>-Glucosamine","year":2020,"lang":"en","type":"article","venue":"Biochemistry","topic":"Studies on Chitinases and Chitosanases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Norges Forskningsråd","keywords":"Chitinase; N-Acetylglucosamine; Chemistry; Acetylation; Serratia marcescens; Enzyme; Biochemistry; Glucosamine; Chitin; Glycoside hydrolase; Stereochemistry; Escherichia coli; Chitosan","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001125653,0.0005094265,0.0005756751,0.00003502294,0.0001507877,0.00005237582,0.0004192221,0.0002197125,0.00000680962],"category_scores_gemma":[0.002540652,0.0004535288,0.000162073,0.0002247986,0.0003280896,0.000009840955,0.0003909096,0.0001845323,0.000004073161],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000136592,"about_ca_system_score_gemma":0.0000984531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000263482,"about_ca_topic_score_gemma":0.00001040664,"domain_scores_codex":[0.9977717,0.00003366666,0.0005072104,0.0008165665,0.0003432124,0.0005276744],"domain_scores_gemma":[0.9982993,0.0003387613,0.0004073318,0.0005031024,0.000124873,0.0003266519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003029247,0.0001246813,0.006481748,0.0007637368,0.0003354212,0.00002028541,0.0002002292,0.00002042523,0.985148,0.00001059784,0.006066337,0.0007983053],"study_design_scores_gemma":[0.0008184055,0.0003459361,0.001622635,0.00017266,0.0001402009,0.00007515604,0.00260674,0.000171586,0.9905862,0.000006762621,0.003309215,0.0001444817],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909689,0.004937042,0.000147859,0.000215562,0.00005864038,0.0002205249,0.0002072023,0.00005446826,0.003189748],"genre_scores_gemma":[0.9954838,0.000944136,0.001763795,0.0004993324,0.00072924,0.00006411559,0.0001613618,0.00007620047,0.0002780544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005438282,"threshold_uncertainty_score":0.9997916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009019007640352409,"score_gpt":0.212233114556786,"score_spread":0.2032141069164335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}