{"id":"W3098558150","doi":"10.1021/acs.biochem.0c00839","title":"Chemoenzymatic Synthesis of Chito-oligosaccharides with Alternating <i>N</i>-<scp>d</scp>-Acetylglucosamine and <scp>d</scp>-Glucosamine","year":2020,"lang":"en","type":"article","venue":"Biochemistry","topic":"Studies on Chitinases and Chitosanases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Norges Forskningsråd","keywords":"Chitinase; N-Acetylglucosamine; Chemistry; Acetylation; Serratia marcescens; Enzyme; Biochemistry; Glucosamine; Chitin; Glycoside hydrolase; Stereochemistry; Escherichia coli; Chitosan","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001095682,0.0004201222,0.0001626447,0.0001821431,0.00009358031,0.0001508048,0.0001454725,0.0001418672,0.0005539279],"category_scores_gemma":[0.0001037353,0.0001178947,0.0002273267,0.0003040423,0.0001274094,0.0001582084,0.0002017413,0.0004407976,0.0002629636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000233277,"about_ca_system_score_gemma":0.0002470237,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009420723,"about_ca_topic_score_gemma":0.001674791,"domain_scores_codex":[0.9999188,0.000009747358,0.000008932046,0.00001953377,0.00002053746,0.00002244218],"domain_scores_gemma":[0.999945,0.000006187103,0.00001304667,0.000007324601,0.00001199677,0.00001635351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001071959,0.000007998447,0.00004245653,0.00001883399,0.000002717859,0.00001423155,0.000005286263,0.00003733294,0.9990833,0.00005353636,0.00001047147,0.0007130677],"study_design_scores_gemma":[0.000002841139,0.00006502928,0.0004765613,0.000002009228,0.000005818254,0.00003914998,0.000006474953,0.000199841,0.9982942,0.00001337232,0.0008921612,0.000002526246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9809065,0.001187719,0.01354876,0.00006885346,0.00003934741,0.00007257985,0.0005785282,0.000104262,0.003493511],"genre_scores_gemma":[0.9797999,0.001355189,0.01492416,0.00004663243,0.000007343047,0.00004251291,0.001013156,0.00003179112,0.002779318],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009420723,"threshold_uncertainty_score":0.001873136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009019007640352409,"score_gpt":0.212233114556786,"score_spread":0.2032141069164335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}