{"id":"W3098715626","doi":"10.1016/j.chom.2020.10.005","title":"Microbial Metabolite Fortifies the Immune Firewall","year":2020,"lang":"en","type":"letter","venue":"Cell Host & Microbe","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Institute for Advanced Research","funders":"","keywords":"Biology; Immune system; Innate immune system; Metabolite; Kupffer cell; Microbiology; Cell; Cell biology; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001859636,0.0005758938,0.0007247204,0.0003849781,0.001477836,0.002492746,0.0008016771,0.01266189,0.003241314],"category_scores_gemma":[0.005040258,0.0003163998,0.0004977657,0.0001540346,0.002384119,0.002450627,0.001574144,0.01327326,0.002013818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001582516,"about_ca_system_score_gemma":0.001013984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008836902,"about_ca_topic_score_gemma":0.00132369,"domain_scores_codex":[0.9993588,0.0001882958,0.00003658576,0.00008264898,0.0002221422,0.0001115197],"domain_scores_gemma":[0.998203,0.0009967093,0.000149756,0.000114718,0.0002362123,0.0002994799],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001464926,0.0001849606,0.001975935,0.0002303398,0.00008147953,0.005910032,0.0002237532,0.0003547636,0.01556763,0.03726513,0.8731565,0.06358463],"study_design_scores_gemma":[0.0004425058,0.000290183,0.001590449,0.0001334603,0.00004493785,0.0024276,0.0003387197,0.001185226,0.01001438,0.06024499,0.9232088,0.00007888207],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.004662189,0.01717834,0.0007357415,0.9230574,0.0481226,0.00001790322,0.00006526244,0.0001182232,0.006042342],"genre_scores_gemma":[0.08317161,0.01730472,0.001261695,0.7791111,0.09873873,0.00008134111,0.00005490614,0.00007474088,0.02020117],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.01266189,"threshold_uncertainty_score":0.011482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009364063994846279,"score_gpt":0.2203891569360522,"score_spread":0.211025092941206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}