{"id":"W3098715626","doi":"10.1016/j.chom.2020.10.005","title":"Microbial Metabolite Fortifies the Immune Firewall","year":2020,"lang":"en","type":"letter","venue":"Cell Host & Microbe","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Institute for Advanced Research","funders":"","keywords":"Biology; Immune system; Innate immune system; Metabolite; Kupffer cell; Microbiology; Cell; Cell biology; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001496227,0.0006493365,0.0006018378,0.00005819468,0.0003419596,0.000143862,0.001084289,0.001041509,0.0001440734],"category_scores_gemma":[0.0000232635,0.0005099128,0.0005794147,0.0001387423,0.0002783603,0.000003895834,0.0005798301,0.00157015,0.0004668385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003513662,"about_ca_system_score_gemma":0.0003456984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001591739,"about_ca_topic_score_gemma":0.00002701982,"domain_scores_codex":[0.997279,0.0001807739,0.0006084781,0.0009259104,0.0001397118,0.0008660557],"domain_scores_gemma":[0.9982745,0.00002735438,0.0003679557,0.001112576,0.0001212166,0.00009638527],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001937887,0.00001517205,0.000007064085,0.0001571717,0.00005852246,0.00002954801,0.0001368023,1.207463e-7,0.5034696,6.991307e-7,0.4960429,0.000062933],"study_design_scores_gemma":[0.0002784087,0.00007164099,0.00006514703,0.00002086528,0.0001032991,0.00004025412,0.00001915137,4.538013e-7,0.362891,0.000005723261,0.6361319,0.0003721326],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.04616328,0.06779347,0.00009109956,0.87667,0.003152869,0.001780228,0.001613299,0.0001064997,0.002629254],"genre_scores_gemma":[0.01481457,0.003598408,0.0003087169,0.9332588,0.008461351,0.00004962317,0.007538147,0.0002472953,0.03172312],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1405787,"threshold_uncertainty_score":0.9997352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009364063994846279,"score_gpt":0.2203891569360522,"score_spread":0.211025092941206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}