{"id":"W3099005773","doi":"10.1101/2020.11.17.20233635","title":"Glutathione as a molecular marker of functional impairment in patients with at-risk mental state: 7-Tesla <sup>1</sup> H-MRS study","year":2020,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"St Joseph's Health Care; Lawson Health Research Institute; Western University","funders":"Schulich School of Medicine and Dentistry; Canadian Institutes of Health Research; Academic Medical Organization of Southwestern Ontario","keywords":"At risk mental state; Glutathione; Schizophrenia (object-oriented programming); Psychosis; Medicine; Clinical psychology; Anterior cingulate cortex; Psychology; Internal medicine; Psychiatry; Cognition; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002362714,0.0003068103,0.0003200477,0.0005319582,0.0004527582,0.0004975086,0.0002102891,0.0004807207,0.001662174],"category_scores_gemma":[0.000587159,0.0001618181,0.0001702562,0.0003132465,0.0002599821,0.000251738,0.0003298347,0.0004160713,0.0003275269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001923274,"about_ca_system_score_gemma":0.0001532628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001378968,"about_ca_topic_score_gemma":0.001508966,"domain_scores_codex":[0.9999204,0.0000221428,0.000009288669,0.00001951443,0.00001256601,0.00001617268],"domain_scores_gemma":[0.9997988,0.00002941267,0.0000625726,0.00002507786,0.00002625204,0.00005785458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003325967,0.0005781543,0.977814,0.00004476967,0.0001466293,0.0009205149,0.000520237,0.00009490864,0.01168953,0.00008986574,0.000222039,0.004553347],"study_design_scores_gemma":[0.00004660178,0.0009360212,0.9963896,0.000005146016,0.00006061439,0.000888236,0.0003530527,0.0002092811,0.0008226463,0.00008436479,0.0001979966,0.000006373374],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995327,0.00009325201,0.00005776614,0.00002178092,0.000002132704,0.00001126591,0.00009205763,0.000002167448,0.0001869316],"genre_scores_gemma":[0.9996225,0.00003654251,0.00007559553,0.00001397082,0.000003904107,0.000007580233,0.0001063029,9.513778e-7,0.0001327734],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001662174,"threshold_uncertainty_score":0.005560517,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01221206678392644,"score_gpt":0.2308815772192379,"score_spread":0.2186695104353115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}