{"id":"W3099426483","doi":"10.1002/ctm2.209","title":"Head and neck cancer: Emerging concepts in biomarker discovery and opportunities for clinical translation","year":2020,"lang":"en","type":"letter","venue":"Clinical and Translational Medicine","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Fundação de Amparo à Pesquisa do Estado de São Paulo; Réseau de Recherche en Santé Buccodentaire et Osseuse","keywords":"Medicine; Head and neck cancer; Radiation therapy; Cancer; Watchful waiting; Biomarker; Oncology; Intensive care medicine; Internal medicine; Prostate cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006599097,0.0003446023,0.001582451,0.0001240531,0.000106486,0.00001649995,0.0000479795,0.00051422,0.00003905577],"category_scores_gemma":[0.0002358302,0.0002588618,0.0001576826,0.00009583212,0.001442337,0.0001337736,0.00001846733,0.00107244,3.312374e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007696854,"about_ca_system_score_gemma":0.0002217315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006397314,"about_ca_topic_score_gemma":0.00008461149,"domain_scores_codex":[0.9970489,0.0001598947,0.001467256,0.0007180588,0.0003235798,0.0002822674],"domain_scores_gemma":[0.9966534,0.00273309,0.0001725308,0.0001134741,0.00008903866,0.0002384601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002069205,0.00009430241,0.2227312,0.002342654,0.0005632954,0.000311214,0.0008375614,1.680364e-7,0.000006878123,0.0001826687,0.2647074,0.5061535],"study_design_scores_gemma":[0.01194182,0.001214962,0.2312925,0.002422306,0.000605792,0.00002427854,0.0001188519,0.000671874,3.970674e-7,0.001064296,0.7503587,0.0002842641],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.03673144,0.04386996,0.0002169308,0.9170868,0.0006387717,0.000807256,0.0002350168,0.00002811578,0.0003856756],"genre_scores_gemma":[0.1115304,0.1599104,0.0007130298,0.7166576,0.009253499,0.0001811056,0.001007312,0.00007703093,0.0006696367],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.5058693,"threshold_uncertainty_score":0.9999864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3549773045546623,"score_gpt":0.4870270505439243,"score_spread":0.1320497459892619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}