{"id":"W3099450297","doi":"10.1101/378109","title":"Autoimmunity to hypocretin and molecular mimicry to flu antigens in Type 1 narcolepsy","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institutes of Health","keywords":"Narcolepsy; Molecular mimicry; Epitope; Autoimmunity; Antigen; Immunology; Immunodominance; Biology; T-cell receptor; Immune system; T cell; Virology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001926488,0.0002903103,0.0002035948,0.0008694826,0.0002838939,0.0002042941,0.0001309797,0.0004012658,0.001451933],"category_scores_gemma":[0.0003035259,0.0002099656,0.0002145115,0.0001922018,0.0002169406,0.0001056536,0.0001991535,0.0001814935,0.0002037282],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002236706,"about_ca_system_score_gemma":0.00007285753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001687786,"about_ca_topic_score_gemma":0.00173551,"domain_scores_codex":[0.9998779,0.00002725819,0.00001303141,0.00003082953,0.00002812935,0.0000227886],"domain_scores_gemma":[0.9998727,0.00002551053,0.0000379562,0.00001012728,0.00001891916,0.00003485509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002198578,0.0001958335,0.6753559,0.000196427,0.0001310468,0.0248345,0.0007183875,0.000194168,0.2870824,0.00006370851,0.0005870237,0.008442108],"study_design_scores_gemma":[0.00002271528,0.000489786,0.9706388,0.00001349873,0.00004756313,0.02355135,0.0001628052,0.0001896258,0.004404786,0.00004090867,0.0004338339,0.000004364699],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991942,0.0003187961,0.00005184507,0.00001669429,0.000004232385,0.000005901176,0.0000316002,0.000005603898,0.0003710895],"genre_scores_gemma":[0.9994993,0.0001481218,0.0000438848,0.00002058531,0.000009615092,0.000002191812,0.00006400431,0.000001562777,0.0002107857],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001687786,"threshold_uncertainty_score":0.004857242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03057070413362006,"score_gpt":0.2738826466143454,"score_spread":0.2433119424807253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}