{"id":"W3099871382","doi":"10.3390/cancers12113437","title":"The Anti-Cancer Properties of the HIV Protease Inhibitor Nelfinavir","year":2020,"lang":"en","type":"review","venue":"Cancers","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canada Foundation for Innovation; McGill University; Rivkin Center for Ovarian Cancer","keywords":"Nelfinavir; Medicine; Cancer; Pharmacology; Protease inhibitor (pharmacology); Proteasome inhibitor; Cancer cell; Cancer research; Immunology; Internal medicine; Viral load; Human immunodeficiency virus (HIV); Multiple myeloma; Antiretroviral therapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002734202,0.0007400756,0.0009427345,0.001815588,0.0003159682,0.0009308707,0.0005733163,0.0006930633,0.005856282],"category_scores_gemma":[0.0003327987,0.0002000308,0.0004645612,0.001690611,0.0003213559,0.001049179,0.0005463108,0.00140494,0.002511928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004432383,"about_ca_system_score_gemma":0.0007871651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000878982,"about_ca_topic_score_gemma":0.001514294,"domain_scores_codex":[0.9998869,0.00001867045,0.00001337784,0.0000231872,0.00004337653,0.0000144769],"domain_scores_gemma":[0.9998413,0.00007275636,0.00002414203,0.00000669763,0.00004217756,0.00001277018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005304252,0.00005554098,0.0001073266,0.01365518,0.00006097924,0.000134656,0.00004462595,0.0003030765,0.003792763,0.00350171,0.01723864,0.9610525],"study_design_scores_gemma":[0.000007779021,0.00005668927,0.0003004934,0.001436981,0.00005441692,0.0006718424,0.00002904683,0.00006056375,0.0007584665,0.00115043,0.9954641,0.000009056781],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002506551,0.9960414,0.0002358757,0.0002154426,0.0001480159,0.00000956729,0.00004529682,0.00001524542,0.003038442],"genre_scores_gemma":[0.001445306,0.996636,0.0002758921,0.0001512499,0.00008329682,0.000008505273,0.00005466888,0.000002067047,0.001342909],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005856282,"threshold_uncertainty_score":0.01959121,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0498168082396987,"score_gpt":0.3031307749004941,"score_spread":0.2533139666607954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}