{"id":"W3099871382","doi":"10.3390/cancers12113437","title":"The Anti-Cancer Properties of the HIV Protease Inhibitor Nelfinavir","year":2020,"lang":"en","type":"review","venue":"Cancers","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canada Foundation for Innovation; McGill University; Rivkin Center for Ovarian Cancer","keywords":"Nelfinavir; Medicine; Cancer; Pharmacology; Protease inhibitor (pharmacology); Proteasome inhibitor; Cancer cell; Cancer research; Immunology; Internal medicine; Viral load; Human immunodeficiency virus (HIV); Multiple myeloma; Antiretroviral therapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000107911,0.0003388551,0.001062478,0.00003524586,0.000170966,0.00002047894,0.0002697524,0.0001125033,0.00004311108],"category_scores_gemma":[0.0001159161,0.0001348284,0.0004473506,0.0003550956,0.0002400058,0.00002720779,0.0001057764,0.0003373446,0.00007066139],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001436585,"about_ca_system_score_gemma":0.00779767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003074533,"about_ca_topic_score_gemma":0.000007852107,"domain_scores_codex":[0.9985507,0.00008575062,0.0004501899,0.0002986136,0.0003435423,0.0002711672],"domain_scores_gemma":[0.9989973,0.00002923869,0.0003233383,0.0004294212,0.00007530942,0.0001453853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005041648,0.00002553511,0.0001262842,0.01569,0.000968734,0.00002014673,0.0005109892,0.00000122832,0.00001748335,0.00002889621,0.04902108,0.9335392],"study_design_scores_gemma":[0.000358277,0.00001981857,0.000003868833,0.02030392,0.001027287,0.000006914912,0.00006888519,0.000003563564,0.0005025844,0.000001022513,0.9775554,0.0001484731],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000107427,0.9924601,4.194117e-7,0.003443442,0.000415186,0.002874887,0.00005917711,0.00002973535,0.0006096143],"genre_scores_gemma":[0.000114412,0.9717496,0.00001873263,0.0001201632,0.0003457966,0.001331852,0.00001609038,0.00004950401,0.02625384],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9333907,"threshold_uncertainty_score":0.9978272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0498168082396987,"score_gpt":0.3031307749004941,"score_spread":0.2533139666607954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}