{"id":"W3100034761","doi":"10.1161/circ.142.suppl_3.13912","title":"Abstract 13912: 17-Beta-Estradiol Directly Regulates Microtubule Dynamics: New Insights Into Sex-Differences in Right Ventricular Function in Pulmonary Hypertension","year":2020,"lang":"en","type":"article","venue":"Circulation","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Microtubule; Internal medicine; Medicine; Pressure overload; Total internal reflection fluorescence microscope; Endocrinology; Tubulin; Microtubule polymerization; Pulmonary hypertension; Cell biology; Biology; Muscle hypertrophy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001501417,0.0003658402,0.0004116262,0.0003173877,0.0002005147,0.0003973231,0.0002391155,0.0003844154,0.005676199],"category_scores_gemma":[0.0001012103,0.0001331447,0.0002893994,0.0002460578,0.0001928252,0.0002836904,0.0001732525,0.0006107457,0.0009340958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002881437,"about_ca_system_score_gemma":0.0002214679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004564351,"about_ca_topic_score_gemma":0.0007462668,"domain_scores_codex":[0.9999442,0.000007636848,0.000005210436,0.00001763852,0.00001453338,0.00001071683],"domain_scores_gemma":[0.9999232,0.000012527,0.00002172308,0.000005147926,0.00001874351,0.00001862789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002070731,0.0001926989,0.004887597,0.001084026,0.00008124051,0.0008448003,0.00009394165,0.0001286326,0.9108265,0.000965384,0.002844491,0.07597996],"study_design_scores_gemma":[0.0005479073,0.003623654,0.3507096,0.0004205696,0.0004229705,0.006010694,0.000344977,0.001439877,0.5343956,0.0021665,0.09984368,0.00007402264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.770355,0.1916028,0.00814441,0.00429582,0.001181145,0.0001194015,0.004998412,0.00044281,0.0188601],"genre_scores_gemma":[0.8972024,0.07064481,0.003402244,0.0009641381,0.001020015,0.0001350626,0.002616162,0.00008855832,0.02392659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005676199,"threshold_uncertainty_score":0.01898879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02832156151888192,"score_gpt":0.2408550205537369,"score_spread":0.212533459034855,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}