{"id":"W3100223696","doi":"10.4049/immunohorizons.2000059","title":"T Cell–Intrinsic CX3CR1 Marks the Most Differentiated Effector CD4+ T Cells, but Is Largely Dispensable for CD4+ T Cell Responses during Chronic Viral Infection","year":2020,"lang":"en","type":"article","venue":"ImmunoHorizons","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CX3CR1; Biology; T cell; Population; CD28; Immunology; Spleen; Effector; Cell biology; Chemokine; Chemokine receptor; Immune system; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0003056349,0.0007002613,0.0007743897,0.0001716208,0.001450371,0.0001273758,0.0007799755,0.0007126983,0.001606547],"category_scores_gemma":[0.000107208,0.0005529369,0.0004972044,0.0004439982,0.0005059417,0.0002141491,0.0004719772,0.001198572,0.002614756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002286151,"about_ca_system_score_gemma":0.0002358254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007159486,"about_ca_topic_score_gemma":0.00005702622,"domain_scores_codex":[0.9961498,0.0007388408,0.0007572683,0.0009238212,0.000101346,0.001328899],"domain_scores_gemma":[0.9978063,0.0006936658,0.0003754697,0.0008923404,0.0001506463,0.00008160515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002051526,0.0004109885,0.0007414705,0.0002238568,0.0004035002,0.00001155907,0.0003982475,0.00001023212,0.9806989,0.00006822145,0.0142597,0.0007217788],"study_design_scores_gemma":[0.005688832,0.001672669,0.003550607,0.00004463919,0.0003186194,0.00003558711,0.0001614898,0.00003735087,0.9097546,0.0000304399,0.07808705,0.0006181258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831471,0.009724802,0.0002890266,0.0009342538,0.002639094,0.001566419,0.0005303677,0.0003779971,0.0007909067],"genre_scores_gemma":[0.979956,0.001045125,0.00002794215,0.0003035068,0.0002757919,0.0002780861,0.0004950271,0.0001187576,0.01749975],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07094432,"threshold_uncertainty_score":0.9998496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009920845604997022,"score_gpt":0.21571395322802,"score_spread":0.2057931076230229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}