{"id":"W3100462444","doi":"10.1182/blood.v130.suppl_1.4934.4934","title":"Comparative Assessment of the Performance of Pharmacokinetic Tools for Prophylactic Dosing of Antihemophilic Factor Recombinant Plasma/Albumin-Free Method (rAHF-PFM) Concentrate in Patients with Hemophilia A","year":2017,"lang":"en","type":"article","venue":"Blood","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; McMaster University; University of Waterloo; Impact; Ottawa Hospital","funders":"","keywords":"Medicine; Dosing; Pharmacokinetics; Recombinant DNA; Albumin; Pharmacology; Internal medicine; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002258518,0.0004986095,0.0008957181,0.0005573991,0.0002253893,0.001103728,0.000338542,0.0006318258,0.0006687686],"category_scores_gemma":[0.01084426,0.0001753743,0.0004835443,0.0004396771,0.0003981226,0.0007162413,0.0003193317,0.0006337711,0.000245155],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005101602,"about_ca_system_score_gemma":0.0005119652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000425408,"about_ca_topic_score_gemma":0.0002430184,"domain_scores_codex":[0.9979824,0.001062742,0.0001360497,0.0002699804,0.0004437763,0.0001050382],"domain_scores_gemma":[0.99575,0.00256885,0.0006970519,0.0002905076,0.0003769766,0.0003166171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2027626,0.004746739,0.4089518,0.000625674,0.001710347,0.0007871531,0.001831455,0.006759039,0.04127422,0.001453685,0.001472746,0.3276246],"study_design_scores_gemma":[0.004176914,0.175387,0.7124791,0.000140143,0.002573838,0.003412873,0.0008456209,0.03693655,0.05704655,0.001145117,0.005685049,0.0001712968],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951539,0.002410595,0.001347645,0.00008551936,0.00002887651,0.00003383538,0.000115576,0.00004453753,0.0007795405],"genre_scores_gemma":[0.9991026,0.000281678,0.0003700229,0.00003085073,0.00001967985,0.00001227249,0.00009014997,0.000006784559,0.0000860185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002258518,"threshold_uncertainty_score":0.01194435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05514829457088596,"score_gpt":0.3674697330272108,"score_spread":0.3123214384563249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}