{"id":"W3100699824","doi":"10.1038/s41418-020-00654-2","title":"Neuronal cell life, death, and axonal degeneration as regulated by the BCL-2 family proteins","year":2020,"lang":"en","type":"review","venue":"Cell Death and Differentiation","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research","keywords":"Programmed cell death; Bcl-2 family; Biology; Necroptosis; Cell biology; Apoptosis; Neuroscience; Degeneration (medical); Neurodegeneration; Axon; Disease; Genetics; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002528233,0.0007729554,0.0008903497,0.001719653,0.0002526136,0.0007746831,0.0006211764,0.0007222326,0.002800032],"category_scores_gemma":[0.0002744029,0.0002106712,0.0002793808,0.001800164,0.0003640946,0.001083014,0.0005988796,0.00142679,0.002200492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006762904,"about_ca_system_score_gemma":0.0007691236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007807033,"about_ca_topic_score_gemma":0.001475793,"domain_scores_codex":[0.9999096,0.00001246771,0.0000123202,0.00001600574,0.0000378805,0.00001175305],"domain_scores_gemma":[0.9999038,0.00003122864,0.00001533066,0.00000424887,0.00002921408,0.00001611946],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007098608,0.0000596142,0.0001043617,0.01179259,0.00004911312,0.0001963412,0.00006055022,0.0003743559,0.00431639,0.005421437,0.03441701,0.9431372],"study_design_scores_gemma":[0.00001107546,0.00007063372,0.0006545029,0.001456987,0.00004019318,0.001037285,0.00003716928,0.00005849094,0.0005679177,0.001830857,0.9942219,0.00001303046],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001547753,0.9973879,0.0001644974,0.0002235325,0.0002530692,0.000004738694,0.00002158873,0.00001352514,0.001776278],"genre_scores_gemma":[0.0005933122,0.9980533,0.000145038,0.000135177,0.0001156154,0.000006898194,0.00003140696,0.000001492615,0.0009176696],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002800032,"threshold_uncertainty_score":0.009366989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01772676234465135,"score_gpt":0.234767960876034,"score_spread":0.2170411985313827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}