{"id":"W3100818137","doi":"10.1002/jbm4.10434","title":"Probing the Scope and Mechanisms of Calcitriol Actions Using Genetically Modified Mouse Models","year":2020,"lang":"en","type":"article","venue":"JBMR Plus","topic":"Vitamin D Research Studies","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Rickets; Calcitriol; Osteomalacia; Phenocopy; Vitamin D and neurology; vitamin D deficiency; Endocrinology; Calcitriol receptor; Internal medicine; Medicine; Biology; Phenotype; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001381325,0.001072741,0.0005673936,0.002190513,0.0005649169,0.001398356,0.001607641,0.001702711,0.004036438],"category_scores_gemma":[0.0004166742,0.0005525218,0.0009384396,0.00050955,0.001773172,0.0009775124,0.0007244111,0.003466489,0.001046452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001011615,"about_ca_system_score_gemma":0.0006950639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001204823,"about_ca_topic_score_gemma":0.001493094,"domain_scores_codex":[0.9988813,0.0002253247,0.0001749038,0.0002658496,0.0002991762,0.000153461],"domain_scores_gemma":[0.9991446,0.0002284799,0.0002744995,0.0001140486,0.0000698551,0.0001686182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004489248,0.0002488465,0.0003716009,0.0001746178,0.00004098618,0.0002545493,0.00006212074,0.0003049507,0.9910257,0.003607954,0.0002567078,0.003202953],"study_design_scores_gemma":[0.0002733482,0.0016768,0.002498763,0.0001702607,0.0001841839,0.001460598,0.0001729175,0.002849763,0.9620366,0.00187781,0.0267504,0.00004856467],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8589955,0.02341097,0.09339835,0.003398282,0.0009500884,0.000907346,0.006569538,0.001686942,0.01068302],"genre_scores_gemma":[0.9066225,0.02045961,0.04786999,0.001142238,0.000238335,0.002022686,0.004826669,0.0004345313,0.01638336],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004036438,"threshold_uncertainty_score":0.01350319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1434588750603689,"score_gpt":0.3488442832019856,"score_spread":0.2053854081416167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}