{"id":"W3100902974","doi":"10.1016/j.clml.2020.11.004","title":"BCL2 Expression in First-Line Diffuse Large B-Cell Lymphoma Identifies a Patient Population With Poor Prognosis","year":2020,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC; University of British Columbia; BC Cancer Agency","funders":"Genentech; Celgene; MorphoSys; H. Lundbeck A/S; Juno Therapeutics; Incyte; F. Hoffmann-La Roche; Alexion Pharmaceuticals; Janssen Pharmaceuticals; Gilead Sciences; AstraZeneca; Bristol-Myers Squibb; TG Therapeutics; Amgen","keywords":"Diffuse large B-cell lymphoma; International Prognostic Index; Hazard ratio; Medicine; Internal medicine; Lymphoma; Immunohistochemistry; Confidence interval; Oncology; Population; Proportional hazards model; Venetoclax; Multivariate analysis; Pathology; Leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006024744,0.0002013548,0.0003709509,0.0006324232,0.000265952,0.0005841138,0.0002407921,0.0003376165,0.0008888957],"category_scores_gemma":[0.001413976,0.0001301596,0.0001169056,0.0004715747,0.0002757885,0.0003456469,0.000368931,0.0003487518,0.0002963332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000273836,"about_ca_system_score_gemma":0.0001620478,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007626826,"about_ca_topic_score_gemma":0.001393668,"domain_scores_codex":[0.9997498,0.00006154587,0.00002205275,0.00007601539,0.00005303254,0.0000375232],"domain_scores_gemma":[0.9994662,0.0001398671,0.0001657193,0.00004949905,0.00007541962,0.0001032255],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003411947,0.00002827986,0.9926773,0.00000998312,0.00001646281,0.0001086842,0.00003519928,0.00008560497,0.003041858,0.00001145368,0.0001035649,0.003540359],"study_design_scores_gemma":[0.00002260528,0.0001700111,0.9967244,0.000004373549,0.00002527715,0.001126782,0.00007632121,0.0005133643,0.0009419505,0.00003812985,0.0003526157,0.000004119641],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992268,0.0002598033,0.0001578045,0.00002357382,0.000002058192,0.000007035175,0.00007756533,0.00000693315,0.0002385003],"genre_scores_gemma":[0.9994401,0.00008432999,0.0001325099,0.0000230687,0.000006733284,0.000006584456,0.0002322881,0.000002231919,0.00007203688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008888957,"threshold_uncertainty_score":0.003186226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02652340087100352,"score_gpt":0.2869746569630959,"score_spread":0.2604512560920924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}