{"id":"W3100962608","doi":"10.1161/circoutcomes.120.007480","title":"Examining the Nocebo Effect of Statins Through Statin Adverse Events Reported in the Food and Drug Administration Adverse Event Reporting System","year":2020,"lang":"en","type":"article","venue":"Circulation Cardiovascular Quality and Outcomes","topic":"Pain Management and Placebo Effect","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Clinical Evaluative Sciences; Institute of Health Services and Policy Research","funders":"","keywords":"Medicine; Adverse effect; Rosuvastatin; Adverse Event Reporting System; Nocebo; Internal medicine; Pravastatin; Odds ratio; Statin; Atorvastatin; Simvastatin; Placebo; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04019058,0.0003055939,0.0006054931,0.004296935,0.0003352597,0.001072166,0.0006645347,0.0004480588,0.001155593],"category_scores_gemma":[0.09100316,0.0002827071,0.001309457,0.005015933,0.0005728809,0.001307313,0.001263904,0.0006137769,0.0002182828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008250162,"about_ca_system_score_gemma":0.0008470801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002889409,"about_ca_topic_score_gemma":0.003340815,"domain_scores_codex":[0.9405255,0.02807347,0.01548227,0.004022307,0.01064771,0.001248717],"domain_scores_gemma":[0.7749776,0.05135697,0.15167,0.006893594,0.01380438,0.001297512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001756635,0.00002128998,0.9957696,0.000153443,0.0002944316,0.00001747017,0.00007755445,0.00005664014,0.00008499472,0.00004161405,0.000142169,0.003165127],"study_design_scores_gemma":[0.00001224138,0.0001423006,0.9984267,0.00008521924,0.0001087362,0.0001222484,0.00008378683,0.0002405243,0.0001422957,0.00003526738,0.0005922288,0.000008505422],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813876,0.006245043,0.003346193,0.0006720821,0.00008951635,0.0003777779,0.00538014,0.00002728265,0.002474362],"genre_scores_gemma":[0.9950318,0.0008526974,0.001449347,0.0002391767,0.0001037715,0.0002304995,0.001926008,0.000008594384,0.000158033],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04019058,"threshold_uncertainty_score":0.2125506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1219260910170862,"score_gpt":0.3373249123363604,"score_spread":0.2153988213192742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}