{"id":"W3101238129","doi":"10.2147/dddt.s259547","title":"<p>Synthesis and Cytotoxic Property of Annonaceous Acetogenin Glycoconjugates</p>","year":2020,"lang":"en","type":"article","venue":"Drug Design Development and Therapy","topic":"Traditional and Medicinal Uses of Annonaceae","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lakehead University","funders":"South China Sea Institute of Oceanology, Chinese Academy of Sciences; Chinese Academy of Sciences; Institute of Oceanology, Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Acetogenin; HeLa; Chemistry; Galactose; Cytotoxicity; MTT assay; Glycoconjugate; Glycosyl; Cell culture; Biochemistry; Stereochemistry; In vitro; Annonaceae; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001988377,0.0002191529,0.0002447965,0.0000370879,0.0001001626,0.00001808861,0.0001331947,0.0000902377,0.00003069781],"category_scores_gemma":[0.0000317504,0.0001521943,0.00004377068,0.00007957158,0.0001426204,0.000008936961,0.0000493619,0.00005781508,0.00000595485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006273657,"about_ca_system_score_gemma":0.0001523271,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001647787,"about_ca_topic_score_gemma":0.000002170916,"domain_scores_codex":[0.9989356,0.00006509255,0.0002455347,0.0003634852,0.000178635,0.0002116334],"domain_scores_gemma":[0.9995227,0.00004011755,0.00008201275,0.0001060988,0.00006858389,0.0001804643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007934678,0.00007160375,0.0003554554,0.00003925701,0.0001525997,0.00001194886,0.0007484786,0.000003690848,0.9508618,0.00007370529,0.003044245,0.04384371],"study_design_scores_gemma":[0.0008205114,0.0003021973,0.001902884,0.00002985502,0.00001157845,0.00002130296,0.0000423731,0.00002334803,0.739702,0.00004814453,0.2568667,0.0002290596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988744,0.008257248,0.0007569354,0.001364955,0.00004063015,0.0003794975,0.00001462572,0.00002140094,0.000420768],"genre_scores_gemma":[0.9877774,0.004943704,0.005499941,0.0008945212,0.0001319454,0.00006280164,0.00004257039,0.00002554672,0.000621613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2538224,"threshold_uncertainty_score":0.6206304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02503340349993544,"score_gpt":0.2164605299789005,"score_spread":0.1914271264789651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}