{"id":"W3101585437","doi":"10.1161/circ.142.suppl_3.14416","title":"Abstract 14416: Mechano-arrhythmogenicity is Enhanced in Late Repolarisation During Acute Ischemia by a Calcium- and TRPA1-dependent Mechanism","year":2020,"lang":"en","type":"article","venue":"Circulation","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Ischemia; Medicine; Hyperkalemia; Sarcomere; Calcium; Myocyte; Diastole; Ryanodine receptor; Internal medicine; Optical mapping; Calpain; Cardiology; Biophysics; Acidosis; Anesthesia; Endocrinology; Chemistry; Biology; Biochemistry; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002101037,0.0003518536,0.0004677584,0.0001537618,0.0001734169,0.0003021116,0.0003403805,0.0004200968,0.007376914],"category_scores_gemma":[0.0001453673,0.0001462906,0.0003651931,0.0002084245,0.0003029956,0.0004105173,0.0002743898,0.0007246956,0.00169342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001868137,"about_ca_system_score_gemma":0.0001728097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002598178,"about_ca_topic_score_gemma":0.0001701658,"domain_scores_codex":[0.9998873,0.000009905276,0.0000194956,0.00003371272,0.00002829579,0.00002122254],"domain_scores_gemma":[0.9998683,0.00001642865,0.00004472194,0.00001270891,0.0000218537,0.00003604259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001783269,0.000017532,0.0001349555,0.00009523648,0.000004127084,0.00006572222,0.00001194301,0.000008545059,0.9983355,0.00003918989,0.0001054782,0.001003437],"study_design_scores_gemma":[0.0001521676,0.001497747,0.03789937,0.00005746485,0.00008462615,0.002065004,0.00006794767,0.0006535895,0.9484299,0.0001860626,0.008894188,0.00001206573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9766122,0.006887049,0.007565523,0.0006555237,0.0002595667,0.00009823717,0.001812988,0.0002533513,0.005855575],"genre_scores_gemma":[0.9779088,0.002694714,0.003891121,0.0002965168,0.0001404254,0.0001402209,0.002353746,0.00008231612,0.0124922],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007376914,"threshold_uncertainty_score":0.02467823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01246760852227644,"score_gpt":0.2490638849957633,"score_spread":0.2365962764734868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}