{"id":"W3101613556","doi":"10.1002/eji.202048687","title":"Splenic erythroid progenitors decrease TNF‐α production by macrophages and reduce systemic inflammation in a mouse model of T cell‐induced colitis","year":2020,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Red pulp; Biology; Spleen; Adoptive cell transfer; Immunology; Inflammation; Tumor necrosis factor alpha; Colitis; Inflammatory bowel disease; Arthritis; Bone marrow; Myeloid; T cell; Internal medicine; Medicine; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000187181,0.000531476,0.0004003593,0.0004100075,0.0001210203,0.000255073,0.0002010287,0.0003828406,0.001024251],"category_scores_gemma":[0.0001340698,0.0001720862,0.0001819685,0.0001423021,0.0002133889,0.0001748947,0.0001327748,0.0009192861,0.0002651572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001203821,"about_ca_system_score_gemma":0.0001701699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002053986,"about_ca_topic_score_gemma":0.0004222065,"domain_scores_codex":[0.9998459,0.00003564339,0.00001597675,0.00002171528,0.00003864318,0.00004218495],"domain_scores_gemma":[0.9998196,0.00001833338,0.00005587934,0.00001906952,0.00001778853,0.00006939324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006456522,0.0003338146,0.0001414595,0.00003850467,0.000005778117,0.0000292832,0.00001446076,0.00006746467,0.9968228,0.00004968857,0.00005158892,0.001799556],"study_design_scores_gemma":[0.0001562856,0.003267398,0.002193979,0.0000151634,0.00002950213,0.0001498099,0.00002362573,0.0007466743,0.9920942,0.00004825393,0.001270912,0.000004251116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948785,0.001510378,0.002000995,0.0001224597,0.00004423166,0.00004760336,0.0002410274,0.0001458308,0.001008933],"genre_scores_gemma":[0.9899709,0.00135676,0.003440726,0.0001022715,0.00002820668,0.0001144273,0.0004126355,0.00004420301,0.004529919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001024251,"threshold_uncertainty_score":0.003426433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01488751313986482,"score_gpt":0.2101160222846895,"score_spread":0.1952285091448246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}