{"id":"W3101668228","doi":"10.1016/j.molcel.2020.11.028","title":"Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2","year":2020,"lang":"en","type":"article","venue":"Molecular Cell","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Center for Advancing Translational Sciences; National Institute of General Medical Sciences; Pulmonary Fibrosis Foundation; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; National Health and Medical Research Council; National Institute on Aging; C3.ai Digital Transformation Institute; National Science Foundation; National Institutes of Health; Massachusetts Consortium on Pathogen Readiness","keywords":"Biology; Host (biology); Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Virology; Coronavirus disease 2019 (COVID-19); Sars virus; 2019-20 coronavirus outbreak; Type (biology); Genetics; Ecology; Pathology; Disease; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002150984,0.0001867076,0.0003369605,0.0001762707,0.00006787339,0.00002327046,0.0002463876,0.0001187857,0.00004074024],"category_scores_gemma":[0.0001708274,0.0001867023,0.0001794743,0.0006662758,0.00005923628,0.0000424874,0.0001494461,0.0002630898,0.000710206],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006631046,"about_ca_system_score_gemma":0.0002830576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009921627,"about_ca_topic_score_gemma":0.000004720551,"domain_scores_codex":[0.9982917,0.0001125742,0.0002793343,0.0004216887,0.0005296847,0.0003650133],"domain_scores_gemma":[0.9990962,0.00004365365,0.00006245889,0.0004876006,0.0002223543,0.00008772129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008918002,0.0001416303,0.0009883072,0.0001780708,0.00003706936,0.0004845069,0.000261211,0.000001337246,0.994409,0.00002978073,0.002457811,0.0001194815],"study_design_scores_gemma":[0.0007128954,0.0009586177,0.0003474643,0.00002451513,0.00005246935,0.000006937849,0.00005712124,0.00003502186,0.8279938,0.00001584232,0.1696528,0.0001424666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892848,0.0005221011,0.0004343016,0.0006162181,0.00007250666,0.0004736268,0.00001426167,0.00006260742,0.008519592],"genre_scores_gemma":[0.9494972,0.000003725233,0.0005594603,0.04954522,0.00008312616,0.0000150083,0.000005720284,0.00005409465,0.0002364893],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.167195,"threshold_uncertainty_score":0.9128499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04667203224472007,"score_gpt":0.3406889250218824,"score_spread":0.2940168927771624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}