{"id":"W3101668228","doi":"10.1016/j.molcel.2020.11.028","title":"Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2","year":2020,"lang":"en","type":"article","venue":"Molecular Cell","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Center for Advancing Translational Sciences; National Institute of General Medical Sciences; Pulmonary Fibrosis Foundation; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; National Health and Medical Research Council; National Institute on Aging; C3.ai Digital Transformation Institute; National Science Foundation; National Institutes of Health; Massachusetts Consortium on Pathogen Readiness","keywords":"Biology; Host (biology); Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Virology; Coronavirus disease 2019 (COVID-19); Sars virus; 2019-20 coronavirus outbreak; Type (biology); Genetics; Ecology; Pathology; Disease; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004142644,0.00054383,0.0003061815,0.0002801047,0.0003157016,0.0004453901,0.0001847944,0.0003721476,0.006090821],"category_scores_gemma":[0.0003078971,0.0001509704,0.0004545167,0.0002456539,0.0002850191,0.0002521538,0.0002755932,0.0006409578,0.0006956901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002396195,"about_ca_system_score_gemma":0.0002467313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007276675,"about_ca_topic_score_gemma":0.0007104984,"domain_scores_codex":[0.999556,0.0001615883,0.00003642071,0.0000424524,0.00007979603,0.0001236615],"domain_scores_gemma":[0.9997563,0.0001247672,0.00001462116,0.00004039553,0.00003370924,0.00003016954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001066897,0.0001665495,0.0007956528,0.00005230895,0.00001351096,0.0002440852,0.00009395188,0.000139597,0.9958242,0.0002575101,0.0001233113,0.001222438],"study_design_scores_gemma":[0.000208118,0.003320816,0.03310327,0.0000156697,0.00003648328,0.0007869623,0.000394452,0.001682586,0.9564481,0.0002009168,0.003789841,0.00001275214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994165,0.0008562684,0.0008987884,0.00009577809,0.00006517915,0.00004860838,0.0006385958,0.00002113476,0.003210671],"genre_scores_gemma":[0.994767,0.0005331867,0.0006158029,0.00008737258,0.00004267684,0.00007260579,0.001432146,0.00000730787,0.002441947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006090821,"threshold_uncertainty_score":0.02037585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04667203224472007,"score_gpt":0.3406889250218824,"score_spread":0.2940168927771624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}