{"id":"W3102223165","doi":"10.1055/a-1282-2264","title":"Insights from the Hereditary Thrombotic Thrombocytopenic Purpura Registry: Discussion of Key Findings Based on Individual Cases from Switzerland","year":2020,"lang":"en","type":"article","venue":"Hämostaseologie","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Mach-Gaensslen Foundation of Canada; Baxalta; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"ADAMTS13; Medicine; Thrombotic thrombocytopenic purpura; Cohort; Pediatrics; Internal medicine; Platelet","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001062193,0.0003702605,0.0006349155,0.00004846284,0.0002916982,0.00003586719,0.001000679,0.0002465645,0.002657115],"category_scores_gemma":[0.0009155014,0.0002005676,0.0001927934,0.0002248425,0.0004716082,0.0001125904,0.0004226566,0.0003930661,0.000396726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005161649,"about_ca_system_score_gemma":0.0001845961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00102866,"about_ca_topic_score_gemma":0.0001704396,"domain_scores_codex":[0.997601,0.0006086378,0.0005824942,0.0006561595,0.0001827418,0.0003689844],"domain_scores_gemma":[0.9965543,0.002170888,0.0002998756,0.000853198,0.00005234846,0.0000694098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.003518789,0.001186808,0.233286,0.0001459204,0.001794075,0.0008327808,0.004258893,0.0003408452,0.1899154,0.0009317289,0.5612638,0.00252493],"study_design_scores_gemma":[0.008356582,0.002516382,0.8369856,0.000845822,0.00106057,0.00002403337,0.007237368,0.0002108534,0.1120548,0.002381722,0.027149,0.001177245],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9828565,0.002720065,0.00007122649,0.006422135,0.0007246675,0.0006684728,0.006166357,0.0001464687,0.0002240775],"genre_scores_gemma":[0.9924175,0.00002064862,0.00008620565,0.001859339,0.0001385175,0.00004062854,0.005379785,0.00002747977,0.00002985477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6036996,"threshold_uncertainty_score":0.9982546,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06311291644864925,"score_gpt":0.2707494601543713,"score_spread":0.207636543705722,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}