{"id":"W3102435291","doi":"10.1002/mds.28392","title":"Fosmetpantotenate Randomized Controlled Trial in Pantothenate Kinase–Associated Neurodegeneration","year":2020,"lang":"en","type":"article","venue":"Movement Disorders","topic":"Neurological diseases and metabolism","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; Toronto Western Hospital; University of Toronto","funders":"","keywords":"Placebo; Medicine; Randomized controlled trial; Internal medicine; Adverse effect; Clinical endpoint; Physical therapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00252008,0.001463667,0.00398663,0.0004881744,0.0004828499,0.001181258,0.000913552,0.002014439,0.01018125],"category_scores_gemma":[0.002935812,0.0006340004,0.001874075,0.0005448618,0.0009361989,0.001126072,0.0004383865,0.002397344,0.0009278592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007151561,"about_ca_system_score_gemma":0.001268164,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009447168,"about_ca_topic_score_gemma":0.002466578,"domain_scores_codex":[0.9989807,0.0005762447,0.00009627775,0.0001530366,0.00007808939,0.0001156757],"domain_scores_gemma":[0.998793,0.0003625015,0.0003017796,0.00008291441,0.0001607254,0.0002989544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9911712,0.00124535,0.0001505522,0.0007782785,0.0005944058,0.00001980879,0.00001619985,0.000076904,0.0008782972,0.00006375425,0.0005024461,0.004502713],"study_design_scores_gemma":[0.9880212,0.01064115,0.0004444543,0.00003153078,0.0002644936,0.00001015451,0.000007688976,0.00008563862,0.00008156815,0.00005108749,0.0003566134,0.000004266946],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9437004,0.02660011,0.001274309,0.00273979,0.003585926,0.01261212,0.003568217,0.0002824258,0.005636691],"genre_scores_gemma":[0.9611936,0.01097691,0.002299903,0.002459701,0.001578126,0.01285367,0.002088901,0.00003917874,0.006510058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01018125,"threshold_uncertainty_score":0.03405964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0236931429818692,"score_gpt":0.2469967193594781,"score_spread":0.2233035763776089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}