{"id":"W3102435291","doi":"10.1002/mds.28392","title":"Fosmetpantotenate Randomized Controlled Trial in Pantothenate Kinase–Associated Neurodegeneration","year":2020,"lang":"en","type":"article","venue":"Movement Disorders","topic":"Neurological diseases and metabolism","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; Toronto Western Hospital; University of Toronto","funders":"","keywords":"Placebo; Medicine; Randomized controlled trial; Internal medicine; Adverse effect; Clinical endpoint; Physical therapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004679608,0.0002657699,0.001037909,0.00009355745,0.000101093,0.00008331851,0.000248897,0.00006893295,0.00019174],"category_scores_gemma":[0.004756546,0.0001922584,0.0004634127,0.0003838896,0.00010296,0.00014064,0.00007394882,0.0001932537,0.00003055441],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001972447,"about_ca_system_score_gemma":0.00003311542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004928742,"about_ca_topic_score_gemma":0.00002413669,"domain_scores_codex":[0.9965046,0.001279917,0.000711624,0.0006126098,0.0004499188,0.0004413202],"domain_scores_gemma":[0.998867,0.000514505,0.0002616761,0.0001620292,0.00001937695,0.000175427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.932469,0.0006918501,0.00004899238,0.000007878607,0.00002468211,0.00002528604,0.0001722772,0.001403557,0.05622572,0.007567942,0.0003082427,0.001054622],"study_design_scores_gemma":[0.9514961,0.000284476,0.0001485603,0.000004138221,0.00006681174,1.346071e-8,0.00001970608,0.0243072,0.00279313,0.02040381,0.0002557658,0.00022028],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9759947,0.0001570669,0.0003271911,0.01356313,0.0005784163,0.006642309,0.00002150121,0.0001625347,0.002553137],"genre_scores_gemma":[0.9454305,0.0005681885,0.000006927905,0.0528681,0.00006872447,0.0008631212,0.000007247694,0.00002440365,0.000162764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05343259,"threshold_uncertainty_score":0.7840072,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0236931429818692,"score_gpt":0.2469967193594781,"score_spread":0.2233035763776089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}