{"id":"W3102456690","doi":"10.1126/science.abf1675","title":"Drugs from bugs in creatures of the sea","year":2020,"lang":"en","type":"letter","venue":"Science","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Creatures; Microbiome; Biology; Antifungal; Natural product; Natural (archaeology); Bacteria; Zoology; Computational biology; Microbiology; Bioinformatics; Genetics; Paleontology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001334051,0.0005303664,0.0007373141,0.0003447416,0.002458934,0.001961719,0.0006743322,0.03007166,0.003955394],"category_scores_gemma":[0.008626046,0.0004235584,0.000727272,0.0002636387,0.002039391,0.00224181,0.0008559581,0.02039633,0.002814115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002634294,"about_ca_system_score_gemma":0.001537551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004700092,"about_ca_topic_score_gemma":0.00935582,"domain_scores_codex":[0.9988648,0.0004389789,0.0001055318,0.0001115095,0.0003253186,0.0001539671],"domain_scores_gemma":[0.9964197,0.002194239,0.0002548169,0.0001049208,0.0003768813,0.0006494739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001571547,0.00008969883,0.001751079,0.00009509026,0.00003777822,0.007057665,0.0003264854,0.0000805873,0.0008679127,0.005013653,0.9655955,0.01892754],"study_design_scores_gemma":[0.0002108049,0.0002086702,0.002272414,0.0002604652,0.00004705164,0.005839963,0.0008496307,0.0004462321,0.0006686458,0.01384078,0.9753019,0.00005340197],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001235842,0.002285831,0.00008670885,0.9845616,0.007555279,0.000009076864,0.0000263296,0.00001712834,0.004222143],"genre_scores_gemma":[0.009606465,0.001606417,0.000162265,0.9588541,0.02238927,0.00001618649,0.00001554975,0.00001550849,0.007334284],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03007166,"threshold_uncertainty_score":0.01911318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01514810932161086,"score_gpt":0.2725088712932222,"score_spread":0.2573607619716113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}