{"id":"W3102502247","doi":"10.25251/skin.4.supp.75","title":"Tapinarof Cream 1% QD for the Treatment of Plaque Psoriasis: Efficacy and Safety in Two Pivotal Phase 3 Trials","year":2020,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Phytochemistry Medicinal Plant Applications","field":"Agricultural and Biological Sciences","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Innovaderm (Canada); Probity Medical Research; University of British Columbia","funders":"","keywords":"Plaque psoriasis; Psoriasis; Medicine; Dermatology; Phase (matter); Clinical trial; Internal medicine; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001956882,0.001442965,0.002008034,0.0003759977,0.0003737327,0.001240442,0.0007004694,0.001819896,0.006825051],"category_scores_gemma":[0.001309038,0.0005507972,0.001925687,0.0004374024,0.0007424321,0.0009586447,0.000227281,0.003031943,0.001242758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000619286,"about_ca_system_score_gemma":0.0009851204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008698977,"about_ca_topic_score_gemma":0.002732509,"domain_scores_codex":[0.9996444,0.0001510465,0.000020264,0.00005419082,0.00005216269,0.00007793877],"domain_scores_gemma":[0.9992167,0.0002665368,0.0001505292,0.00006247501,0.00007826561,0.0002254891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7194198,0.02538437,0.00158893,0.005406003,0.003373686,0.0003729928,0.0003765282,0.00161932,0.03808392,0.0006722995,0.0100817,0.1936204],"study_design_scores_gemma":[0.8045804,0.1771709,0.006384299,0.0003869932,0.00122227,0.0003794257,0.00008535675,0.0008642235,0.002033417,0.0005226521,0.006315379,0.00005467131],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9166073,0.05497437,0.002603449,0.003239368,0.0009896685,0.007466379,0.003866946,0.000421879,0.009830725],"genre_scores_gemma":[0.9529811,0.03017393,0.002935666,0.002687459,0.000507233,0.003233714,0.002485376,0.00007213152,0.004923393],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006825051,"threshold_uncertainty_score":0.0228321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06043474788367265,"score_gpt":0.3426864154785979,"score_spread":0.2822516675949253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}