{"id":"W3102551131","doi":"10.1016/j.ecoenv.2020.111588","title":"Evaluation of general stress, detoxification pathways, and genotoxicity in rainbow trout exposed to rare earth elements dysprosium and lutetium","year":2020,"lang":"en","type":"article","venue":"Ecotoxicology and Environmental Safety","topic":"Heavy Metal Exposure and Toxicity","field":"Environmental Science","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Environment and Climate Change Canada","funders":"Environment and Climate Change Canada; Natural Sciences and Engineering Research Council of Canada; Chugoku Marine Paints","keywords":"Metallothionein; Oxidative stress; Lutetium; Chemistry; Superoxide dismutase; Catalase; DNA damage; Genotoxicity; Toxicity; Lipid peroxidation; Biochemistry; Biology; DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001230373,0.0002660948,0.0002707901,0.000259329,0.0002280766,0.0002390914,0.0001281701,0.0003200898,0.0007793133],"category_scores_gemma":[0.0001092625,0.0001384686,0.0003030589,0.0001709121,0.0002355977,0.0001729567,0.0002553675,0.0003536174,0.000154626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003099709,"about_ca_system_score_gemma":0.0003826414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002616317,"about_ca_topic_score_gemma":0.004388068,"domain_scores_codex":[0.9999176,0.000009025204,0.000006774816,0.00002611365,0.00002228372,0.00001809575],"domain_scores_gemma":[0.9999089,0.000008107023,0.00002744125,0.000007829351,0.00002587075,0.00002190126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003029493,0.00002682785,0.004565069,0.00004273486,0.00001158826,0.00004151931,0.00006626324,0.00006285698,0.9940873,0.00002435795,0.00001469842,0.0007537969],"study_design_scores_gemma":[0.00004292068,0.006281164,0.1844114,0.00002236447,0.0001747188,0.0003729986,0.0005902014,0.0009418152,0.8045037,0.0002098486,0.002419317,0.00002959778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983754,0.0004219691,0.0005100771,0.00002697685,0.000008363934,0.0000152274,0.0003002597,0.00001245988,0.0003292124],"genre_scores_gemma":[0.9939539,0.0005718259,0.001251675,0.00005603325,0.000004887817,0.00005279462,0.0005789321,0.00001023541,0.003519712],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002616317,"threshold_uncertainty_score":0.005202234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02511019375252764,"score_gpt":0.2317591567727451,"score_spread":0.2066489630202175,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}