{"id":"W3102562966","doi":"10.3390/biom10111567","title":"Transcriptional Profiling Reveals Ribosome Biogenesis, Microtubule Dynamics and Expression of Specific lncRNAs to be Part of a Common Response to Cell-Penetrating Peptides","year":2020,"lang":"en","type":"article","venue":"Biomolecules","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cancerfonden; York University; Vetenskapsrådet; New York University Abu Dhabi; Sheikh Hamdan Bin Rashid Al Maktoum Award for Medical Sciences","keywords":"Ribosome biogenesis; Biology; Cell biology; Biogenesis; Gene; HeLa; Gene expression; Ribosome; Microtubule; Phenotype; RNA; Cell; Gene expression profiling; Ribosome profiling; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001171971,0.0002179717,0.0002659451,0.0002159029,0.0001226883,0.0003031884,0.00009358182,0.0002705627,0.001036137],"category_scores_gemma":[0.0001594629,0.0001247173,0.0002978247,0.0001859789,0.0002264225,0.0001821414,0.0001648441,0.0004789535,0.0003833934],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002194473,"about_ca_system_score_gemma":0.000164722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004124547,"about_ca_topic_score_gemma":0.0006602106,"domain_scores_codex":[0.9998323,0.00001402925,0.00001161076,0.00006812445,0.00003588619,0.00003813815],"domain_scores_gemma":[0.9998559,0.00003344392,0.00004312967,0.00001592905,0.00002154914,0.00003002833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002823863,0.000003422841,0.0001151554,0.000007397286,0.00000101958,0.000009142324,0.000007068846,0.00001116609,0.9996306,0.0000119072,0.000005747441,0.0001691242],"study_design_scores_gemma":[0.000004593595,0.0001809848,0.02947827,0.000005129416,0.00001675655,0.0001220152,0.0000819016,0.0007700862,0.9683447,0.00004408004,0.0009445846,0.000006819691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899195,0.0009841735,0.005331071,0.0001093225,0.00003134581,0.00003339489,0.002112984,0.00009436494,0.001383801],"genre_scores_gemma":[0.9880267,0.0006559597,0.004206433,0.0001599371,0.00001647399,0.0001203988,0.002657097,0.00004777857,0.004109217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001036137,"threshold_uncertainty_score":0.003466249,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02403568667011288,"score_gpt":0.2547657650101998,"score_spread":0.2307300783400869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}