{"id":"W3102562966","doi":"10.3390/biom10111567","title":"Transcriptional Profiling Reveals Ribosome Biogenesis, Microtubule Dynamics and Expression of Specific lncRNAs to be Part of a Common Response to Cell-Penetrating Peptides","year":2020,"lang":"en","type":"article","venue":"Biomolecules","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cancerfonden; York University; Vetenskapsrådet; New York University Abu Dhabi; Sheikh Hamdan Bin Rashid Al Maktoum Award for Medical Sciences","keywords":"Ribosome biogenesis; Biology; Cell biology; Biogenesis; Gene; HeLa; Gene expression; Ribosome; Microtubule; Phenotype; RNA; Cell; Gene expression profiling; Ribosome profiling; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000168551,0.0001546901,0.000207728,0.00006870155,0.00004415913,0.00001646134,0.0001854735,0.00009586849,0.000008230418],"category_scores_gemma":[0.00005005295,0.0001516173,0.00008173583,0.0001133907,0.00006319969,0.000004943607,0.0001057783,0.00003881378,0.000002834879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008644914,"about_ca_system_score_gemma":0.00003869058,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001846908,"about_ca_topic_score_gemma":0.00002500483,"domain_scores_codex":[0.9988861,0.0001043915,0.0003553213,0.0003483036,0.0001365936,0.000169275],"domain_scores_gemma":[0.9994476,0.00001968376,0.00008957119,0.0001996837,0.0001006734,0.0001427824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001064581,0.00005421702,0.001852117,0.000074851,0.00001409991,0.000003098066,0.0002667854,0.00003597106,0.9957195,0.00003443271,0.0006340396,0.0002463332],"study_design_scores_gemma":[0.0002501157,0.0008665159,0.002242416,0.0000875158,0.00001000459,0.000003846997,0.0004553415,0.00003488496,0.9948651,0.000005741083,0.001014185,0.0001643693],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954516,0.001293299,0.001772968,0.0007615802,0.00003887204,0.0002695202,0.0003509646,0.000006820522,0.00005434251],"genre_scores_gemma":[0.9928429,0.000152633,0.006273091,0.0004486913,0.00006059239,0.00001673926,0.0001279326,0.00001845359,0.00005894878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004500122,"threshold_uncertainty_score":0.6182773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02403568667011288,"score_gpt":0.2547657650101998,"score_spread":0.2307300783400869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}