{"id":"W3102624934","doi":"10.1038/s41467-020-19532-z","title":"The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":574,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Japan Science and Technology Agency; Japan Agency for Medical Research and Development; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; University of Dundee; Asahi Glass Foundation; Takeda Science Foundation","keywords":"Degron; Gene knockdown; Mutant; Cell biology; Yeast; Degradation (telecommunications); Saccharomyces cerevisiae; Function (biology); Phenotype; Protein degradation; Auxin; Chemistry; Biology; Gene; Biochemistry; Computer science; Ubiquitin ligase; Ubiquitin","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01217306286600655,"score_gpt":0.2527165831789991,"score_spread":0.2405435203129925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}