{"id":"W3102708391","doi":"10.1016/j.chom.2020.11.003","title":"Integrative Imaging Reveals SARS-CoV-2-Induced Reshaping of Subcellular Morphologies","year":2020,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":344,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Deutsche Forschungsgemeinschaft; Universität Heidelberg; European Molecular Biology Laboratory; Deutsches Zentrum für Infektionsforschung","keywords":"Biology; Golgi apparatus; Cell biology; Endoplasmic reticulum; Organelle; Live cell imaging; Viral replication; Inflammasome; Cell; Biogenesis; Virology; Virus; Inflammation; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000367454,0.0003241857,0.0006735266,0.0002011967,0.00009120792,0.00004432538,0.0004110528,0.0001419026,0.00002513926],"category_scores_gemma":[0.0004666007,0.000276182,0.0002529359,0.0006025233,0.000265845,0.000128998,0.0003086784,0.0006438543,0.0002569306],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001251613,"about_ca_system_score_gemma":0.0002730274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000286288,"about_ca_topic_score_gemma":0.000006978039,"domain_scores_codex":[0.9978296,0.0001280363,0.0005343864,0.0006073836,0.0003443977,0.0005561826],"domain_scores_gemma":[0.9987379,0.0001640286,0.0001957581,0.0005078033,0.0003346854,0.00005984405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002844557,0.0001052954,0.008709115,0.0003643361,0.00004733643,0.0003985915,0.002300878,7.826173e-8,0.9763485,0.00002888224,0.01080124,0.0006112864],"study_design_scores_gemma":[0.001286944,0.000285872,0.0004225234,0.0002495087,0.0000627371,0.0000353795,0.001594027,0.0001259523,0.9647304,0.00005316348,0.03091435,0.0002391127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852148,0.004366923,0.0004489773,0.001825056,0.0001127813,0.0005981112,0.00002116739,0.0001321413,0.007280089],"genre_scores_gemma":[0.9365659,0.00001895977,0.0007355809,0.0623849,0.0001434794,0.00001762255,0.00001159358,0.00005859677,0.00006336621],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06055984,"threshold_uncertainty_score":0.9999691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06330512994992016,"score_gpt":0.338069386959137,"score_spread":0.2747642570092168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}