{"id":"W310296652","doi":"10.1007/978-1-4939-1191-2_12","title":"Lovastatin, Compactin, and Related Anticholesterolemic Agents","year":2014,"lang":"en","type":"book-chapter","venue":"Fungal biology","topic":"Microbial Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Lovastatin; Aspergillus terreus; Polyketide; Reductase; Enzyme; Polyketide synthase; Penicillium citrinum; Chemistry; Biosynthesis; Biochemistry; Coenzyme A; Stereochemistry; Natural product; Nonribosomal peptide; Biology; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009077114,0.0003921595,0.0002827268,0.0005881318,0.0001753189,0.0007021587,0.000331217,0.0003811377,0.006223161],"category_scores_gemma":[0.0001178039,0.0001125433,0.0001712723,0.0005874268,0.0002018332,0.0007590555,0.00032228,0.0006556869,0.004291603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004452008,"about_ca_system_score_gemma":0.0001793215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005165383,"about_ca_topic_score_gemma":0.001498519,"domain_scores_codex":[0.9999399,0.000005924455,0.000003116198,0.00001152897,0.00003093031,0.000008677578],"domain_scores_gemma":[0.9999745,0.000007524107,0.000004032645,0.000002239814,0.000005644644,0.00000608748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002759437,0.000124737,0.0001024996,0.0007656562,0.0000146619,0.0001772803,0.00008768147,0.0003499358,0.1136416,0.03150257,0.05593963,0.7970178],"study_design_scores_gemma":[0.00001083728,0.00008233832,0.0002185127,0.00006012291,0.000008486436,0.0003722631,0.00001852187,0.00009306781,0.01374491,0.003996652,0.9813867,0.000007581322],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.009777275,0.7803164,0.00985972,0.00272058,0.002031025,0.00005857344,0.0004787816,0.0004171493,0.1943405],"genre_scores_gemma":[0.05797612,0.5028909,0.01036911,0.002217044,0.001216099,0.000096114,0.0007179173,0.0001120205,0.4244047],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.006223161,"threshold_uncertainty_score":0.02081859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01129212560792791,"score_gpt":0.2484702073467033,"score_spread":0.2371780817387754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}