{"id":"W3103466171","doi":"10.1002/bies.202000240","title":"The genetic structure of SARS‐CoV‐2 does not rule out a laboratory origin","year":2020,"lang":"en","type":"article","venue":"BioEssays","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Centre of Excellence for Child and Youth Mental Health","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Furin; Biology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus; Genetics; Virology; Mutagenesis; Computational biology; Gene; Coronavirus disease 2019 (COVID-19); Mutation; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001010175,0.0001493102,0.0002514079,0.00004707466,0.00009049434,0.00003269818,0.0002821133,0.0001169331,0.00002294665],"category_scores_gemma":[0.0002724269,0.00008036811,0.00008404437,0.0002767561,0.0002109097,0.00003313873,0.00009271689,0.0002580352,0.00008257913],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003814944,"about_ca_system_score_gemma":0.0003931778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005778074,"about_ca_topic_score_gemma":0.00005563666,"domain_scores_codex":[0.9986477,0.000072613,0.000242614,0.000270676,0.0004732129,0.0002932002],"domain_scores_gemma":[0.9991722,0.0001122721,0.0000713461,0.0004062846,0.0001858105,0.00005213979],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002559042,0.00002638327,0.0219441,0.0001625276,0.00006007992,0.00004102534,0.0004887785,1.015573e-7,0.9721571,0.0002966023,0.002607288,0.001960127],"study_design_scores_gemma":[0.0007244371,0.0001344183,0.004214954,0.00002250018,0.00003309666,0.000002498921,0.0001525239,0.00006727644,0.7634413,0.0001881256,0.2309298,0.0000890412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994221,0.0008438948,0.00004417905,0.003299566,0.0002214619,0.0003088657,0.0001391557,0.00005797838,0.0008639098],"genre_scores_gemma":[0.970508,0.00002155121,0.0002493332,0.02870688,0.0004314754,0.000009802525,0.000002458454,0.00002709375,0.00004336507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2283225,"threshold_uncertainty_score":0.3277316,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04978216513101796,"score_gpt":0.3460525122684599,"score_spread":0.2962703471374419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}