{"id":"W3103533795","doi":"10.1161/hypertensionaha.120.15690","title":"Chromosome 2 Fragment Substitutions in Dahl Salt-Sensitive Rats and RNA Sequencing Identified <i>Enpep</i> and <i>Hs2st1</i> as Vascular Inflammatory Modulators","year":2020,"lang":"en","type":"article","venue":"Hypertension","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Lady Davis Institute for Medical Research; National Institutes of Health; Government of Canada; Compute Canada","keywords":"Inflammation; Proinflammatory cytokine; Congenic; Biology; Endocrinology; Internal medicine; Molecular biology; Gene; Blood pressure; Chromosome; Immunology; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001509466,0.0005270962,0.0002616579,0.0005098694,0.0001643753,0.0001775876,0.0002169067,0.0003405102,0.002401458],"category_scores_gemma":[0.0001536311,0.0002537199,0.0004779946,0.0002488244,0.0002574585,0.00009868205,0.0002016728,0.0004574832,0.0003404393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001967381,"about_ca_system_score_gemma":0.0001599266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001430084,"about_ca_topic_score_gemma":0.00314419,"domain_scores_codex":[0.9997858,0.00002868469,0.00001937666,0.00008477993,0.00004641089,0.00003493879],"domain_scores_gemma":[0.9997832,0.00003021902,0.0001000848,0.00001979171,0.0000132192,0.00005349534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003137625,0.00003009772,0.0005470207,0.00001166416,0.00001140496,0.00007473187,0.00001377497,0.00003237669,0.9982603,0.00004227359,0.00002097082,0.0006414833],"study_design_scores_gemma":[0.0002562056,0.002548025,0.1049546,0.00002664077,0.000225035,0.002070058,0.0001749466,0.001940572,0.8814523,0.0001196769,0.006187831,0.00004401109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946728,0.0002038755,0.00331086,0.00006273764,0.00003729702,0.00003662017,0.001158476,0.000056993,0.000460272],"genre_scores_gemma":[0.9839486,0.000521388,0.005969375,0.000130454,0.0000247541,0.0001178392,0.003842794,0.0001029155,0.005341894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002401458,"threshold_uncertainty_score":0.008033693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02418690529868119,"score_gpt":0.2335981593816107,"score_spread":0.2094112540829295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}