{"id":"W3103697444","doi":"10.3390/ijns6040091","title":"Newborn Screening for Mucopolysaccharidosis I: Moving Forward Learning from Experience","year":2020,"lang":"en","type":"article","venue":"International Journal of Neonatal Screening","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"","keywords":"Newborn screening; Mucopolysaccharidosis; Medicine; Biomarker; Enzyme replacement therapy; Pediatrics; Disease; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01842299,0.0005817239,0.001125395,0.0009834423,0.001519843,0.00412911,0.002216971,0.007170983,0.004007548],"category_scores_gemma":[0.0589491,0.0002812658,0.0009100903,0.0005029133,0.003685339,0.00924054,0.004133676,0.01104634,0.001624313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003005357,"about_ca_system_score_gemma":0.008944246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003923558,"about_ca_topic_score_gemma":0.01134383,"domain_scores_codex":[0.989972,0.005588534,0.0009382313,0.0007925006,0.002119273,0.0005894028],"domain_scores_gemma":[0.9441043,0.03897018,0.001665723,0.0009308322,0.009302661,0.005026365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008753801,0.00008118138,0.001922574,0.002354427,0.00005132591,0.002321281,0.003668643,0.0002797924,0.0005599513,0.01564062,0.6113593,0.3616734],"study_design_scores_gemma":[0.00003203348,0.000242491,0.001423878,0.007804719,0.00005623455,0.004328396,0.005103006,0.0002844822,0.0004151317,0.0257208,0.9544972,0.00009159737],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001153598,0.0707358,0.003567446,0.8762612,0.04270897,0.0000323372,0.00003963904,0.00007620788,0.005424726],"genre_scores_gemma":[0.02552047,0.2380594,0.009762331,0.6071587,0.1130495,0.0001116793,0.00009902394,0.0001162424,0.006122644],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01842299,"threshold_uncertainty_score":0.09743124,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06334219266723634,"score_gpt":0.3413471169501007,"score_spread":0.2780049242828643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}