{"id":"W3103727622","doi":"10.25251/skin.4.supp.83","title":"Efficacy and Safety of Bimekizumab in Patients with Moderate to Severe Plaque Psoriasis: Results from BE READY, a 56-Week Phase 3, Randomized, Double-Blinded, Placebo-Controlled Study with Randomized Withdrawal","year":2020,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Double blinded; Medicine; Randomized controlled trial; Placebo; Plaque psoriasis; Psoriasis; Internal medicine; Dermatology; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002742321,0.001102942,0.003838022,0.0003963671,0.0006444425,0.001217288,0.0008214817,0.002244381,0.005415265],"category_scores_gemma":[0.002169327,0.00079837,0.002361489,0.0003626171,0.001335091,0.001442863,0.0004050757,0.00366304,0.001035899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004227629,"about_ca_system_score_gemma":0.0008848727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005068881,"about_ca_topic_score_gemma":0.000908591,"domain_scores_codex":[0.9991078,0.0004527543,0.00006456114,0.0001280803,0.0001022566,0.0001445076],"domain_scores_gemma":[0.9987004,0.0004121489,0.0002893728,0.000131132,0.00009447292,0.0003723358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9556406,0.007326066,0.0007636426,0.0008979152,0.0008503885,0.00004011655,0.00006093043,0.0002058266,0.006281197,0.0000879496,0.0008660291,0.02697943],"study_design_scores_gemma":[0.9131942,0.08172454,0.003161744,0.0000463088,0.0004302783,0.00004400917,0.00002410566,0.0001906675,0.0005631836,0.0001243555,0.000480153,0.00001640826],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9784437,0.01296036,0.0009414945,0.000885829,0.00048536,0.002659939,0.001070493,0.0001594295,0.002393379],"genre_scores_gemma":[0.9886445,0.003461457,0.001475224,0.001442499,0.0004992346,0.00190211,0.0007595703,0.00003800471,0.001777437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005415265,"threshold_uncertainty_score":0.01811588,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01612960875211718,"score_gpt":0.2519932776894991,"score_spread":0.235863668937382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}