{"id":"W3103727622","doi":"10.25251/skin.4.supp.83","title":"Efficacy and Safety of Bimekizumab in Patients with Moderate to Severe Plaque Psoriasis: Results from BE READY, a 56-Week Phase 3, Randomized, Double-Blinded, Placebo-Controlled Study with Randomized Withdrawal","year":2020,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Double blinded; Medicine; Randomized controlled trial; Placebo; Plaque psoriasis; Psoriasis; Internal medicine; Dermatology; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002414402,0.0004993215,0.003712914,0.0002693876,0.0001505884,0.00001506969,0.0003541936,0.0001679137,0.00007327519],"category_scores_gemma":[0.0009585858,0.0002225247,0.000173052,0.000341233,0.0005073912,0.00009598711,0.00005668477,0.0004993076,0.000004703052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005387553,"about_ca_system_score_gemma":0.0001910886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000478766,"about_ca_topic_score_gemma":0.0002201681,"domain_scores_codex":[0.9946034,0.002440937,0.001889665,0.0003714657,0.0003408316,0.0003536854],"domain_scores_gemma":[0.9922407,0.005374141,0.001518222,0.0003426424,0.0003802566,0.0001440818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9653864,0.001688792,0.0001030141,0.00001221163,0.007073859,0.0003067539,0.02179032,0.000941129,0.0002174047,0.000009593879,0.0002451829,0.00222537],"study_design_scores_gemma":[0.975984,0.01415357,0.00008790965,0.0004447607,0.005724695,0.0004385614,0.00228731,0.00005449407,0.0005009716,0.00002788509,0.00005166679,0.0002441668],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891524,0.001423657,0.0002223981,0.002610014,0.0002448216,0.006031259,0.000116174,0.00001720765,0.0001820288],"genre_scores_gemma":[0.9988465,0.000325641,0.0001556113,0.0002574671,0.0001505197,0.00005313452,0.00007827565,0.00003745696,0.00009544214],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01950301,"threshold_uncertainty_score":0.9074293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01612960875211718,"score_gpt":0.2519932776894991,"score_spread":0.235863668937382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}