{"id":"W3103858600","doi":"10.1080/23723556.2020.1818537","title":"A single-molecule view of telomerase regulation at telomeres","year":2020,"lang":"en","type":"article","venue":"Molecular & Cellular Oncology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research","keywords":"Telomerase; Telomere; Cajal body; Biogenesis; Telomerase RNA component; Cell biology; RNA; Biology; Cancer research; Telomerase reverse transcriptase; DNA; Genetics; Gene; RNA splicing","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002064965,0.0002571135,0.0003372846,0.0003199665,0.0004014724,0.0006011428,0.0007260134,0.001112916,0.00227078],"category_scores_gemma":[0.0001556433,0.0002917511,0.0003235244,0.0001486564,0.0004604654,0.001534931,0.0002807158,0.001751145,0.0008392712],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004902848,"about_ca_system_score_gemma":0.0002138867,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005801188,"about_ca_topic_score_gemma":0.0008358525,"domain_scores_codex":[0.9999274,0.000004597568,0.000002861217,0.00002640178,0.00002720352,0.00001154858],"domain_scores_gemma":[0.9999102,0.00003087696,0.00001175004,0.00001032053,0.0000132275,0.00002355366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006064877,0.00002354324,0.0001324306,0.0001374924,0.00000964436,0.0001957912,0.00004550804,0.0007983593,0.9770474,0.01319768,0.001260644,0.00709082],"study_design_scores_gemma":[0.00006963717,0.000315594,0.004298528,0.00008344563,0.00008503564,0.001693183,0.0001751102,0.02942882,0.7956094,0.02277856,0.1453853,0.00007755071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4313635,0.1966827,0.2744581,0.02917169,0.004712711,0.00009309971,0.002440062,0.002156844,0.05892133],"genre_scores_gemma":[0.8413031,0.06080178,0.06584406,0.002364251,0.001507434,0.000133401,0.0005036354,0.0001043149,0.02743796],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00227078,"threshold_uncertainty_score":0.007596552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02919206950906748,"score_gpt":0.2706078848601938,"score_spread":0.2414158153511264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}