{"id":"W3103967727","doi":"10.1111/cup.13918","title":"<i><scp>MAP2K1</scp>‐</i>driven mixed Langerhans cell histiocytosis, Rosai‐Dorfman‐Destombes disease and Erdheim‐Chester disease, clonally related to acute myeloid leukemia","year":2020,"lang":"en","type":"article","venue":"Journal of Cutaneous Pathology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Hospital Foundation","funders":"","keywords":"Erdheim–Chester disease; Histiocytosis; Langerhans cell histiocytosis; Histiocyte; Rosai–Dorfman disease; Medicine; Pathology; Malignancy; Pathological; Disease; Myeloid; Malignant histiocytosis; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001089237,0.0003815313,0.000822736,0.0001990551,0.0001214841,0.00004276014,0.0002099943,0.0001762727,0.00005226138],"category_scores_gemma":[0.0003983443,0.0003195667,0.0002817314,0.000238778,0.0001739704,0.0001060946,0.0001046649,0.0004646387,0.0001486336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002643933,"about_ca_system_score_gemma":0.0006144432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004875514,"about_ca_topic_score_gemma":0.00000727621,"domain_scores_codex":[0.9977444,0.0001337998,0.0007441341,0.0004547668,0.0004518003,0.0004710973],"domain_scores_gemma":[0.9972073,0.0001865644,0.0003931678,0.0002880366,0.0002319284,0.001692958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"not_applicable","study_design_scores_codex":[0.009580406,0.002969731,0.2224622,0.001064447,0.002916718,0.5340794,0.01198734,0.001425437,0.0721747,0.0005295429,0.1298795,0.01093059],"study_design_scores_gemma":[0.0428558,0.02899032,0.3732066,0.0019367,0.02960217,0.09079181,0.002229764,0.00282187,0.00542868,0.00512549,0.41478,0.002230836],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98985,0.003196389,0.0002906411,0.004472835,0.0003550446,0.0004410472,0.0001693052,0.0000623503,0.001162397],"genre_scores_gemma":[0.9901559,0.0009081865,0.001709522,0.004300945,0.0002020715,0.00001422673,0.00006815539,0.00007561684,0.002565345],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4432876,"threshold_uncertainty_score":0.9999256,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009231692505738529,"score_gpt":0.2341491543786435,"score_spread":0.224917461872905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}