{"id":"W3104483740","doi":"10.1101/2020.04.01.020941","title":"LxxIxE-like Motif in Spike Protein of SARS-CoV-2 that is Known to Recruit the Host PP2A-B56 Phosphatase Mimics Artepillin C, an Immunomodulator, of Brazilian Green Propolis","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Bee Products Chemical Analysis","field":"Agricultural and Biological Sciences","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Université Laval","keywords":"Protein phosphatase 2; Cytokine storm; Biology; Protein subunit; Glycoprotein; Phosphatase; Coronavirus; Cell biology; Virology; Coronavirus disease 2019 (COVID-19); Genetics; Gene; Infectious disease (medical specialty); Phosphorylation; Medicine; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004369693,0.0002520966,0.00015062,0.0001561894,0.00009705717,0.0001027113,0.00008431117,0.0001799002,0.00167999],"category_scores_gemma":[0.00006588588,0.00006973158,0.0002861982,0.0001133128,0.0001073572,0.0001062333,0.0001342089,0.0001806386,0.0003800914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001693967,"about_ca_system_score_gemma":0.0001089243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004723237,"about_ca_topic_score_gemma":0.0005529064,"domain_scores_codex":[0.999959,0.000008255468,0.000002509905,0.000008660456,0.00001296488,0.000008576375],"domain_scores_gemma":[0.9999727,0.000003193312,0.00001135515,0.000002095359,0.000002515098,0.000008168745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001246642,0.000007933662,0.0003360853,0.00003638812,0.000006916505,0.0001236746,0.000004902386,0.00009662552,0.9982387,0.00008881582,0.00004015172,0.0008950884],"study_design_scores_gemma":[0.00004591245,0.0004227711,0.01372509,0.00001309977,0.00003130339,0.001090951,0.00003414263,0.002230459,0.9746892,0.0001219591,0.007586211,0.000008972214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935457,0.001940071,0.002658144,0.0001004863,0.00002698964,0.00002201501,0.0003440801,0.00004868678,0.001313785],"genre_scores_gemma":[0.9951993,0.0005249843,0.00170712,0.00005956779,0.000006218197,0.00001409479,0.0006575245,0.000008961079,0.001822307],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00167999,"threshold_uncertainty_score":0.005620122,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04279966159511921,"score_gpt":0.241131523037837,"score_spread":0.1983318614427178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}