{"id":"W3104671901","doi":"10.1128/aac.01135-20","title":"Adverse Events Associated with Nifurtimox Treatment for Chagas Disease in Children and Adults","year":2020,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Nifurtimox; Chagas disease; Medicine; Benznidazole; Adverse effect; Drug; Disease; Intensive care medicine; Pharmacology; Internal medicine; Trypanosoma cruzi; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000986909,0.0001011012,0.0002293151,0.0002363746,0.0001182488,0.0001776674,0.00006514163,0.00015132,0.003009379],"category_scores_gemma":[0.004076945,0.00004419206,0.0002515612,0.0003244417,0.0001206308,0.0001668133,0.0001316637,0.0003527917,0.0001631206],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002614888,"about_ca_system_score_gemma":0.0002947342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001122396,"about_ca_topic_score_gemma":0.002689719,"domain_scores_codex":[0.9993123,0.0002827292,0.00009402748,0.00005289086,0.0002003568,0.00005775681],"domain_scores_gemma":[0.9969801,0.001078166,0.00156608,0.00005849852,0.000161649,0.0001554988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002087226,0.0001575585,0.8161082,0.001173347,0.0003500021,0.001102014,0.0002897698,0.00009243835,0.001744098,0.0001700502,0.005312517,0.1714129],"study_design_scores_gemma":[0.00009001424,0.001038525,0.9872434,0.000244332,0.0001346546,0.003854961,0.0001240786,0.00009217858,0.0003506255,0.00005286479,0.006769272,0.000005125637],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9395367,0.04315145,0.0007736739,0.001065175,0.0001066358,0.000180914,0.002003785,0.00004054306,0.0131412],"genre_scores_gemma":[0.9930496,0.004686107,0.000656145,0.0002919461,0.0000786563,0.00005803874,0.0004972455,0.00000372512,0.0006785158],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003009379,"threshold_uncertainty_score":0.0100674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01706385139776317,"score_gpt":0.2707427604790908,"score_spread":0.2536789090813277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}