{"id":"W3105043026","doi":"10.1093/oso/9780199965724.003.0054","title":"Stereocontrolled C-N Ring Construction: The Pyne Synthesis of Hyacinthacine B 3","year":2013,"lang":"en","type":"book-chapter","venue":"Oxford University Press eBooks","topic":"Synthesis of β-Lactam Compounds","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Aziridine; Pyrrolidine; Azetidine; Chemistry; Amide; Cycloaddition; Imine; Thioamide; Ring (chemistry); Stereochemistry; Enantioselective synthesis; Ligand (biochemistry); Enamine; Medicinal chemistry; Organic chemistry; Catalysis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001358556,0.0005483915,0.0009200679,0.0001581672,0.0002595159,0.00005728075,0.001078237,0.0005334324,0.001869953],"category_scores_gemma":[0.00005543824,0.0004909232,0.0004945173,0.000009121318,0.0006469234,0.0001159386,0.0004905281,0.0006017901,0.000006465952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001960208,"about_ca_system_score_gemma":0.00008487335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009110787,"about_ca_topic_score_gemma":0.00001042727,"domain_scores_codex":[0.9982011,0.00004024461,0.0004383287,0.0005272931,0.0004542211,0.0003387902],"domain_scores_gemma":[0.99671,0.0008928775,0.000780255,0.001258037,0.0002258431,0.0001329736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001534557,0.00008543158,0.0001092705,0.001363141,0.004914026,0.0001930866,0.0004508417,0.00002170705,0.00897985,0.8262361,0.003432621,0.1526794],"study_design_scores_gemma":[0.001047552,0.0000200084,0.000007001893,0.0006262159,0.0008543544,0.00004285786,0.0002201903,0.0000978484,0.02486799,0.0005539011,0.9711283,0.0005337814],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.002987517,0.0001105276,0.00003657356,0.00005626843,0.0001485724,0.0003026437,0.0001342262,0.000152559,0.9960711],"genre_scores_gemma":[0.06021021,0.0001531838,0.0005077107,0.00001446773,0.0002373693,0.000005288601,0.000008575144,0.00008814393,0.9387751],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.9676957,"threshold_uncertainty_score":0.9997543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01596249498219781,"score_gpt":0.1801074684953522,"score_spread":0.1641449735131544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}