{"id":"W3105842719","doi":"10.15252/msb.20209888","title":"Gene expression profiling reveals insights into infant immunological and febrile responses to group B meningococcal vaccine","year":2020,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Medical Research Council; European Commission; NIHR Oxford Biomedical Research Centre; University of Oxford; National Institute for Health and Care Research; UK Research and Innovation; FP7 Ideas: European Research Council; Wellcome Trust; GlaxoSmithKline","keywords":"Reactogenicity; Vaccination; Immunogenicity; Meningococcal vaccine; Neisseria meningitidis; Immunology; Biology; Gene expression profiling; Medicine; Gene expression; Immunization; Immune system; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002179632,0.0002626561,0.0005545628,0.0001340895,0.0002284012,0.00003364483,0.0001883338,0.000475704,0.00005525884],"category_scores_gemma":[0.000358809,0.0001957609,0.00007028179,0.0002040706,0.00005023537,0.00005455691,0.0003529839,0.0002453438,0.0001421277],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002538723,"about_ca_system_score_gemma":0.00002019656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002141509,"about_ca_topic_score_gemma":0.000004438687,"domain_scores_codex":[0.9977057,0.0008555896,0.000486231,0.0005908904,0.00001566861,0.0003458981],"domain_scores_gemma":[0.9992889,0.0001035724,0.0001706681,0.0002754563,0.00008035493,0.00008106182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006054228,0.00003426128,0.005576063,0.00002925715,0.00009242593,0.00001085784,0.000325132,0.000003364073,0.9909292,0.001661097,0.0002469748,0.000485942],"study_design_scores_gemma":[0.001366809,0.001664081,0.006026612,0.00006500911,0.00003278337,0.0001843348,0.0001509321,0.00001629718,0.9475397,0.00009720897,0.04248662,0.0003695424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9817435,0.0114076,0.004600682,0.0005327259,0.0008336915,0.0006731135,0.00001692088,0.0001473158,0.0000444876],"genre_scores_gemma":[0.9984694,0.00009324326,0.0006018864,0.0003320633,0.0001254318,0.0001673065,0.0001334344,0.00002196206,0.00005534505],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04338944,"threshold_uncertainty_score":0.7982897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01546478811707907,"score_gpt":0.2542413682925274,"score_spread":0.2387765801754483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}