{"id":"W3106071946","doi":"10.3390/bios10110184","title":"Drug-Based Gold Nanoparticles Overgrowth for Enhanced SPR Biosensing of Doxycycline","year":2020,"lang":"en","type":"article","venue":"Biosensors","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Regroupement Québécois sur les Matériaux de Pointe","funders":"Natural Sciences and Engineering Research Council of Canada; Higher Education Commision, Pakistan","keywords":"Doxycycline; Biosensor; Surface plasmon resonance; Analyte; Colloidal gold; Nanotechnology; Drug; Chemistry; Nanoparticle; Materials science; Combinatorial chemistry; Chromatography; Pharmacology; Antibiotics; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001329938,0.0002244249,0.000307686,0.00005487662,0.00005453902,0.00001418284,0.0001453318,0.0001356479,0.000001319439],"category_scores_gemma":[0.0002882573,0.000200755,0.0002594354,0.0002348622,0.0001656621,0.000004179087,0.00005150119,0.00005856917,0.000002319912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001013491,"about_ca_system_score_gemma":0.00004436792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007009355,"about_ca_topic_score_gemma":0.00001396619,"domain_scores_codex":[0.9986499,0.0000509094,0.0003865807,0.0004757771,0.0001488521,0.0002879825],"domain_scores_gemma":[0.9991339,0.00004022912,0.0002166711,0.000306781,0.0001764865,0.000125935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004009287,0.00006007685,0.0001414981,0.00004645571,0.00004931215,0.000001419552,0.00002368233,0.00004831953,0.996108,0.00003023721,0.001390854,0.001699215],"study_design_scores_gemma":[0.0006118146,0.000443342,0.0001063104,0.00002871699,0.00005743448,0.000001210658,0.00006960944,0.0006857847,0.9921647,0.00003611174,0.005532958,0.0002619776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939457,0.0001564674,0.004134212,0.001147678,0.0000521176,0.0002731607,0.00008253162,0.00007878106,0.0001294116],"genre_scores_gemma":[0.974566,0.00005137279,0.02399173,0.0009356673,0.00023168,0.000005455891,0.00009447934,0.000035059,0.00008857156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01985752,"threshold_uncertainty_score":0.818655,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01482428914195886,"score_gpt":0.2660695088649147,"score_spread":0.2512452197229558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}