{"id":"W3106103044","doi":"10.1111/jth.15171","title":"Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion","year":2020,"lang":"en","type":"article","venue":"Journal of Thrombosis and Haemostasis","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Regional Laboratory Medicine Program; Thrombosis and Atherosclerosis Research Institute; St. Michael's Hospital; Canadian Blood Services; University of Toronto; Queen's University; McMaster University","funders":"Canadian Institutes of Health Research; British Heart Foundation; Wellcome Trust; Heart and Stroke Foundation of Canada","keywords":"Platelet; In vivo; Platelet adhesion; Platelet adhesiveness; Adhesion; Function (biology); Chemistry; Cell biology; Platelet aggregation; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002131126,0.0002132648,0.0001489433,0.0002300287,0.0000952878,0.0002163662,0.0001529195,0.0002262171,0.001652486],"category_scores_gemma":[0.0002850982,0.00008112902,0.0001109809,0.00007295396,0.0001213287,0.0001064034,0.0001730522,0.0003612605,0.0002427885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001918616,"about_ca_system_score_gemma":0.00009122524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002753734,"about_ca_topic_score_gemma":0.0004382145,"domain_scores_codex":[0.9998393,0.00005602447,0.000009114145,0.00002171628,0.00004508081,0.00002886784],"domain_scores_gemma":[0.9998177,0.00003678551,0.00006061239,0.00001321198,0.0000170767,0.00005463244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000154561,0.00002989722,0.001084319,0.00003362143,0.00001044619,0.00005807623,0.000009976337,0.00004607669,0.9965504,0.00005530664,0.00006288593,0.001904344],"study_design_scores_gemma":[0.00004940605,0.001747806,0.06346057,0.00002508734,0.00005602782,0.002084357,0.00004562742,0.001576472,0.9274263,0.0001320852,0.003389586,0.000006607456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964527,0.001205963,0.001238425,0.00007967204,0.000009137559,0.00001213045,0.00005980908,0.00002439612,0.0009177217],"genre_scores_gemma":[0.9973227,0.000415285,0.001441634,0.00004146803,0.00001085462,0.00001183672,0.00015167,0.000006597531,0.0005979894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001652486,"threshold_uncertainty_score":0.005528092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04981762575770654,"score_gpt":0.2996616970780129,"score_spread":0.2498440713203063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}