{"id":"W3106177555","doi":"10.25251/skin.4.supp.70","title":"Roflumilast Cream (ARQ-151) 0.15% and 0.3% Improved Burden of Signs and Symptoms in Adults With Chronic Plaque Psoriasis in a Phase 2b Study","year":2020,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Probity Medical Research","funders":"","keywords":"Plaque psoriasis; Medicine; Roflumilast; Dermatology; Psoriasis; Pediatrics; Internal medicine; COPD","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001722582,0.001187843,0.002094263,0.0003191765,0.0003702621,0.0007076626,0.0006922012,0.00136791,0.005241158],"category_scores_gemma":[0.0007472272,0.0005780325,0.001329793,0.00030732,0.0006685357,0.0008114587,0.0002368687,0.002748667,0.001129282],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004451293,"about_ca_system_score_gemma":0.0006968287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001287141,"about_ca_topic_score_gemma":0.002954877,"domain_scores_codex":[0.9995174,0.0002178305,0.00002555799,0.00007263623,0.0000493079,0.0001172437],"domain_scores_gemma":[0.9995536,0.000113871,0.00006698395,0.00004601251,0.00003996672,0.0001796062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7646841,0.06017382,0.003580795,0.001669887,0.002274945,0.0002919674,0.0002606916,0.0008291554,0.05019479,0.0002224872,0.00515175,0.1106657],"study_design_scores_gemma":[0.6455039,0.3333183,0.01594353,0.00006044299,0.000743369,0.0002311166,0.00005304425,0.0004370818,0.001645034,0.0001032187,0.00193322,0.00002777305],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869974,0.006191306,0.0003449222,0.0006142345,0.0001925363,0.001521711,0.001091996,0.0001642927,0.002881551],"genre_scores_gemma":[0.9884112,0.003646711,0.001042536,0.001078271,0.0003117108,0.001045912,0.001411392,0.00003631974,0.003016036],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005241158,"threshold_uncertainty_score":0.01753342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008240515777240696,"score_gpt":0.2363785252162527,"score_spread":0.228138009439012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}