{"id":"W3106598165","doi":"10.1021/acssynbio.0c00415","title":"Curli-Mediated Self-Assembly of a Fibrous Protein Scaffold for Hydroxyapatite Mineralization","year":2020,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"Supramolecular Self-Assembly in Materials","field":"Materials Science","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Office of Naval Research; Northwestern University; Canada Foundation for Innovation; Natural Sciences and Engineering Research Council of Canada; Air Force Office of Scientific Research; Faculty of Engineering, McGill University","keywords":"Biomineralization; Peptide; Protein subunit; Self-assembly; Supramolecular chemistry; Monomer; Biophysics; Chemistry; Mineralization (soil science); Nanotechnology; Nanofiber; Materials science; Biochemistry; Crystallography; Biology; Polymer; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001648636,0.000340903,0.0002416594,0.0001600735,0.0001423739,0.0002238392,0.0002688335,0.0004654381,0.0004530255],"category_scores_gemma":[0.0001408615,0.0001538247,0.000344418,0.0001058674,0.0001792305,0.000233364,0.0002866072,0.0004015566,0.0003243675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003508892,"about_ca_system_score_gemma":0.0002045672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006877745,"about_ca_topic_score_gemma":0.001094381,"domain_scores_codex":[0.999832,0.00001290632,0.00001414133,0.00003885098,0.00006091279,0.00004104977],"domain_scores_gemma":[0.9999025,0.00001184422,0.00003419685,0.000009889559,0.00001941915,0.00002217626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000005377077,0.000005158185,0.00001910988,0.00001852483,0.000002196181,0.00002193154,0.000009502893,0.00007335788,0.9993537,0.00003176698,0.00001251289,0.0004469145],"study_design_scores_gemma":[0.000003089417,0.0000450686,0.0004146015,0.000002081047,0.00000427142,0.00006395639,0.000006016853,0.001309517,0.9972101,0.00001548183,0.0009199204,0.000005889548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9714969,0.001393193,0.02409847,0.00009020344,0.00005508979,0.00008178561,0.0002347788,0.000371466,0.002178087],"genre_scores_gemma":[0.9831487,0.0005006703,0.01409521,0.00005236212,0.000009789807,0.00004878416,0.0002102137,0.00004432065,0.00188992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006877745,"threshold_uncertainty_score":0.002545893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.015637628419599,"score_gpt":0.2491951498997529,"score_spread":0.233557521480154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}