{"id":"W3107099586","doi":"10.1192/j.eurpsy.2020.105","title":"High-sensitive C-reactive protein and homocysteine levels in patients with newly diagnosed bipolar disorder, their first-degree relatives, and healthy control persons—Results from a clinical study","year":2020,"lang":"en","type":"article","venue":"European Psychiatry","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"Horizon 2020 Framework Programme; Allergan; H. Lundbeck A/S; Gangstedfonden; Canadian Institutes of Health Research; Sunovion; Danmarks Frie Forskningsfond; Novo Nordisk; Region Hovedstaden; Lundbeckfonden; National Natural Science Foundation of China; Cilag; Innovationsfonden; Pfizer; Markedsmodningsfonden; Sundhed og Sygdom, Det Frie Forskningsråd; Helsefonden; Purdue University","keywords":"Homocysteine; Bipolar disorder; First-degree relatives; Medicine; Internal medicine; Plasma homocysteine; Psychiatry; Lithium (medication); Family history","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003112356,0.0003953046,0.0007007205,0.00007875728,0.0001555896,0.00003117569,0.00008018258,0.00007431891,0.000006332876],"category_scores_gemma":[0.0001675106,0.0002787424,0.00006456118,0.0002328541,0.0001532179,0.0001226138,0.0000757737,0.0006028711,0.00001545389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003163139,"about_ca_system_score_gemma":0.0001012509,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008615597,"about_ca_topic_score_gemma":0.001977716,"domain_scores_codex":[0.9971134,0.0008305349,0.0006151088,0.0008917082,0.0002453826,0.0003038797],"domain_scores_gemma":[0.998663,0.0002804602,0.0002581431,0.0003395828,0.00006994195,0.0003888716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01039847,0.003439746,0.9632643,0.0000307236,0.0005494768,0.00007123734,0.01351465,0.000001165331,0.000003185825,0.00001463795,0.00005829382,0.008654059],"study_design_scores_gemma":[0.08397289,0.01146896,0.8984749,0.0002654788,0.0002252044,0.000002701612,0.004838048,0.00004256546,0.000001072002,0.00001219696,0.0004458269,0.000250114],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837431,0.005830835,0.0001017207,0.005781915,0.0001070861,0.00328653,0.0009237577,0.00006962175,0.0001554242],"genre_scores_gemma":[0.9978566,0.00003394378,0.001004367,0.0006825611,0.0001851935,0.00002750001,0.000116384,0.00007613144,0.00001730714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07357442,"threshold_uncertainty_score":0.9999665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02458056537104582,"score_gpt":0.2540582443426943,"score_spread":0.2294776789716484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}