{"id":"W3107119770","doi":"10.3389/fmicb.2020.577762","title":"The Human Microbiome as a Focus of Antibiotic Discovery: Neisseria mucosa Displays Activity Against Neisseria gonorrhoeae","year":2020,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Concordia University of Edmonton; Wellcome Trust; National Science Foundation","keywords":"Neisseria gonorrhoeae; Microbiology; Antimicrobial; Biology; Microbiome; Human Microbiome Project; Antibiotic resistance; Neisseria; Human pathogen; Antibiotics; Human microbiome; Bacteria; Bioinformatics; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001028484,0.0002650523,0.0002533046,0.0001412552,0.0004085844,0.0008173044,0.0002965593,0.000502403,0.002330472],"category_scores_gemma":[0.000734281,0.0001272356,0.0002263426,0.000131067,0.0003062302,0.0003440186,0.001153051,0.0005201728,0.0003834325],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002100527,"about_ca_system_score_gemma":0.0009928429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004676083,"about_ca_topic_score_gemma":0.000883468,"domain_scores_codex":[0.9994134,0.0002732647,0.00001871839,0.00008446473,0.0001231683,0.00008707116],"domain_scores_gemma":[0.9996423,0.0000647232,0.00004366555,0.00004119181,0.00004105458,0.0001671252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002425881,0.0004059507,0.006016089,0.0001336227,0.000007979533,0.000148303,0.0004193005,0.0001274494,0.9419714,0.0004567538,0.0003136582,0.049757],"study_design_scores_gemma":[0.000115405,0.00953533,0.05659384,0.000140183,0.00006956272,0.001502784,0.001953282,0.001603345,0.8937213,0.0007610726,0.03396051,0.00004332053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9795136,0.0008093025,0.01288574,0.001069048,0.00006224432,0.0003554683,0.0001866494,0.0001222659,0.004995647],"genre_scores_gemma":[0.931487,0.001476423,0.06100765,0.0004297665,0.00003099029,0.0003469438,0.0002050715,0.00002867139,0.004987426],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002330472,"threshold_uncertainty_score":0.007796228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01206453368159438,"score_gpt":0.2652742728579656,"score_spread":0.2532097391763712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}