{"id":"W3107167263","doi":"10.1155/2020/8814989","title":"In Vitro Induction of Pluripotency from Equine Fibroblasts in 20% or 5% Oxygen","year":2020,"lang":"en","type":"article","venue":"Stem Cells International","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Homeobox protein NANOG; SOX2; Reprogramming; Biology; Cell biology; Embryonic stem cell; Endoderm; Oxygen tension; Embryoid body; Induced pluripotent stem cell; Germ layer; Molecular biology; Chemistry; Cell; Biochemistry; Gene; Oxygen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001222804,0.0001240707,0.0001621488,0.0001116816,0.00001028306,0.00001299238,0.0003776742,0.000127468,0.0002983445],"category_scores_gemma":[0.00003199046,0.0001181228,0.00005866805,0.000166255,0.00004134468,0.00001427035,0.0002384066,0.0001470443,0.0000459651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004769568,"about_ca_system_score_gemma":0.00009296446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001134286,"about_ca_topic_score_gemma":0.00009405797,"domain_scores_codex":[0.9986755,0.00006944883,0.0003717665,0.0003760981,0.0003140361,0.0001931567],"domain_scores_gemma":[0.9995716,0.00002292578,0.00009920709,0.0001565155,0.00007859006,0.00007117043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001004866,0.00008139703,0.0004230404,0.00002791476,0.00003417823,0.00002617631,0.0001240295,0.0005453537,0.9953816,0.000008107895,0.001089908,0.001253451],"study_design_scores_gemma":[0.001151134,0.0001809686,0.0005373564,0.00003131414,0.000002438017,0.000002972467,0.00009140663,0.001584901,0.9847112,0.00004847252,0.01153546,0.0001224076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952906,0.0002558448,0.0004062427,0.001443248,0.0003830067,0.0002166049,0.0002098067,0.000006213374,0.001788416],"genre_scores_gemma":[0.9962825,0.0001368914,0.000539676,0.0001793076,0.000311536,0.00001512595,0.0002062132,0.00001781968,0.00231096],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01067041,"threshold_uncertainty_score":0.4816906,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02282304274563062,"score_gpt":0.2713491136470864,"score_spread":0.2485260709014558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}