{"id":"W3107167263","doi":"10.1155/2020/8814989","title":"In Vitro Induction of Pluripotency from Equine Fibroblasts in 20% or 5% Oxygen","year":2020,"lang":"en","type":"article","venue":"Stem Cells International","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Homeobox protein NANOG; SOX2; Reprogramming; Biology; Cell biology; Embryonic stem cell; Endoderm; Oxygen tension; Embryoid body; Induced pluripotent stem cell; Germ layer; Molecular biology; Chemistry; Cell; Biochemistry; Gene; Oxygen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004429817,0.0004298761,0.0003750063,0.0002637493,0.0003644368,0.0002529062,0.0002625025,0.0003058054,0.002110933],"category_scores_gemma":[0.0001832056,0.0001606475,0.0004533626,0.0002460529,0.0001781784,0.000206366,0.0004018975,0.0004536659,0.0005725326],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000142557,"about_ca_system_score_gemma":0.0002195184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008951724,"about_ca_topic_score_gemma":0.001926329,"domain_scores_codex":[0.9996657,0.00004365283,0.00007436879,0.00006255365,0.000104957,0.00004873082],"domain_scores_gemma":[0.9998568,0.00002961897,0.00002298392,0.00002920151,0.00003793168,0.00002341195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001743983,0.00008977952,0.00047249,0.0001521837,0.000009904801,0.0002982846,0.000178227,0.0001242728,0.9953983,0.0001630739,0.0001124073,0.002826653],"study_design_scores_gemma":[0.00004317176,0.001148711,0.007624368,0.00004948147,0.00006666363,0.0006646801,0.0001066856,0.0009016347,0.9730059,0.0001204706,0.01625143,0.00001673656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9744601,0.003171723,0.01027487,0.00009101765,0.0001698884,0.0004129719,0.001310532,0.00007967612,0.01002918],"genre_scores_gemma":[0.9581235,0.003901545,0.01652016,0.0003050542,0.00007263426,0.0009645758,0.005406084,0.00006258558,0.01464384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002110933,"threshold_uncertainty_score":0.007061779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02282304274563062,"score_gpt":0.2713491136470864,"score_spread":0.2485260709014558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}