{"id":"W3107337141","doi":"10.1016/j.annonc.2020.10.441","title":"221P Patient-reported sexual and urinary function in nonmetastatic castration-resistant prostate cancer (nmCRPC) when treated with apalutamide (APA) vs placebo (PBO) and ongoing androgen deprivation therapy (ADT) in SPARTAN","year":2020,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Janssen Research and Development; Chugai Pharmaceutical; Deutsche Krebshilfe; Astellas Pharma; Ipsen; Clovis Oncology; Eisai; Exelixis; Sanofi; Bristol-Myers Squibb; AstraZeneca; Amgen; Pfizer; Memorial Sloan-Kettering Cancer Center; GlaxoSmithKline","keywords":"Medicine; Sexual function; Prostate cancer; Androgen deprivation therapy; Urology; Internal medicine; Placebo; Cancer; Metastasis; Oncology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005384627,0.000236041,0.0008261014,0.0002391504,0.0001731608,0.000431432,0.0002032013,0.0002804582,0.004152176],"category_scores_gemma":[0.001486477,0.0001357482,0.00116777,0.0002903224,0.0001631634,0.0004330579,0.000220083,0.0007313706,0.0002343947],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002318216,"about_ca_system_score_gemma":0.0003172779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001864309,"about_ca_topic_score_gemma":0.003079658,"domain_scores_codex":[0.9997024,0.000129229,0.00002535291,0.00003291441,0.00004826551,0.00006182762],"domain_scores_gemma":[0.9994552,0.0002080962,0.000107849,0.00002911866,0.00003685194,0.0001629361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4549278,0.006912678,0.4012866,0.000886679,0.006991485,0.0005318646,0.0002698126,0.002121855,0.008372803,0.0002751302,0.004355582,0.1130676],"study_design_scores_gemma":[0.00787537,0.04870925,0.9360273,0.00005406615,0.001800284,0.0004945297,0.0002255624,0.00186339,0.00107924,0.0001857322,0.001639876,0.00004550196],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963647,0.001142459,0.00003945919,0.00008368183,0.0000696181,0.00002702572,0.0007745166,0.00001249675,0.001486172],"genre_scores_gemma":[0.9988239,0.0001909918,0.00003237465,0.00004243604,0.00002197425,0.00001197574,0.0003971863,0.000001228749,0.0004778751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004152176,"threshold_uncertainty_score":0.01389045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0956510077947232,"score_gpt":0.3548784918408807,"score_spread":0.2592274840461575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}