{"id":"W3107469534","doi":"10.1016/j.fertnstert.2020.09.158","title":"Individualized ovarian stimulation for in vitro fertilization: a multicenter, open label, exploratory study with a mixed protocol of follitropin delta and highly purified human menopausal gonadotropin","year":2020,"lang":"en","type":"article","venue":"Fertility and Sterility","topic":"Ovarian function and disorders","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia, Okanagan Campus; Ottawa Fertility Centre; University of British Columbia; Centre Hospitalier de l’Université de Montréal; McGill University; CReATe Fertility Centre; Clinique Paro Excellence","funders":"EMD Serono; Ferring Pharmaceuticals","keywords":"Gonadotropin; Menotropins; In vitro fertilisation; Medicine; Follicle-stimulating hormone; Pregnancy rate; Regimen; Internal medicine; Ovarian hyperstimulation syndrome; Gonadotropin-releasing hormone agonist; Gynecology; Endocrinology; Andrology; Gonadotropin-releasing hormone; Pregnancy; Luteinizing hormone; Ovulation induction; Biology; Ovulation; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002230185,0.001465182,0.003191119,0.0005789365,0.0007032811,0.001000858,0.001223605,0.001101091,0.003532294],"category_scores_gemma":[0.001578445,0.0005586386,0.0009186338,0.0006080191,0.001918133,0.00105223,0.0006741635,0.001859188,0.000386297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008699359,"about_ca_system_score_gemma":0.002096098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007813083,"about_ca_topic_score_gemma":0.0009517043,"domain_scores_codex":[0.9984943,0.0006926317,0.00008503698,0.000298413,0.0001922985,0.0002373664],"domain_scores_gemma":[0.998912,0.0002768889,0.0002068935,0.0001756961,0.00004452633,0.0003840587],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8405299,0.1044091,0.002844646,0.0002370824,0.0004458861,0.00008400986,0.0001828908,0.0009163891,0.01176062,0.0001762304,0.0002743273,0.03813883],"study_design_scores_gemma":[0.2134675,0.7769765,0.00651893,0.00002068045,0.0002698375,0.00007226299,0.0001015626,0.000687708,0.001312509,0.000113173,0.0004322531,0.0000271049],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969622,0.0003528679,0.0006220394,0.00005371051,0.0000432747,0.001518464,0.0001139159,0.00002159621,0.0003120218],"genre_scores_gemma":[0.9892399,0.0005220621,0.004095007,0.0003239057,0.0002425167,0.004569806,0.0003538089,0.0000164898,0.000636405],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003532294,"threshold_uncertainty_score":0.01181668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09076856100118773,"score_gpt":0.3455783327779423,"score_spread":0.2548097717767545,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}