{"id":"W3107506179","doi":"10.1016/j.molmet.2020.101132","title":"Small intestinal taurochenodeoxycholic acid-FXR axis alters local nutrient-sensing glucoregulatory pathways in rats","year":2020,"lang":"en","type":"article","venue":"Molecular Metabolism","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Diabetes Canada; University of Toronto; Toronto General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Endocrinology; Nutrient; Internal medicine; Medicine; Chemistry; Cell biology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003765291,0.001140557,0.0008644612,0.001015213,0.0003769746,0.0004635098,0.0003908711,0.0006938719,0.002519985],"category_scores_gemma":[0.0002509297,0.0005361527,0.00106142,0.000323942,0.0009375678,0.0007102905,0.0004245416,0.002049152,0.0004906396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006461713,"about_ca_system_score_gemma":0.0006768667,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001256012,"about_ca_topic_score_gemma":0.001835234,"domain_scores_codex":[0.9995701,0.00004685918,0.00004242661,0.0001274195,0.00008357217,0.0001296443],"domain_scores_gemma":[0.9996418,0.00002017075,0.000107431,0.00005191169,0.00003540988,0.0001432935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006176345,0.0009653604,0.001986425,0.0001181698,0.00006415525,0.0002224539,0.00008772648,0.0001835568,0.9845057,0.0002651633,0.0002237665,0.005201078],"study_design_scores_gemma":[0.0006847495,0.01374362,0.02416272,0.00005108447,0.0002865739,0.0006317907,0.0004763409,0.002646699,0.9518006,0.0004743964,0.004974142,0.00006729172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927734,0.001528029,0.003530279,0.0003025087,0.0001515214,0.00008338442,0.0005521936,0.0002322542,0.0008465905],"genre_scores_gemma":[0.9864671,0.001772626,0.004411435,0.0003451784,0.00004884623,0.0003704829,0.000826883,0.00007256042,0.005684922],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002519985,"threshold_uncertainty_score":0.008430243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02273083390470762,"score_gpt":0.2200838583835316,"score_spread":0.197353024478824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}