{"id":"W3107508539","doi":"10.3390/metabo10120487","title":"Untargeted Metabolomics and Polyamine Profiling in Serum before and after Surgery in Colorectal Cancer Patients","year":2020,"lang":"en","type":"article","venue":"Metabolites","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Korea Institute of Science and Technology","keywords":"Metabolomics; Colorectal cancer; Medicine; Putrescine; Arginine; Internal medicine; Cancer; Spermidine; Metabolome; Bioinformatics; Oncology; Gastroenterology; Biochemistry; Chemistry; Biology; Enzyme; Amino acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001015942,0.0002296672,0.0003511089,0.0003889537,0.0001387021,0.0002800839,0.00008765224,0.0002301984,0.0004616701],"category_scores_gemma":[0.0002572521,0.00008636349,0.0001568028,0.000473369,0.0001103924,0.0001392492,0.0001623787,0.0002335463,0.0001131109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001310223,"about_ca_system_score_gemma":0.0001515073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007259336,"about_ca_topic_score_gemma":0.001679975,"domain_scores_codex":[0.9998976,0.00002160962,0.000009700173,0.000030542,0.00002157517,0.00001897348],"domain_scores_gemma":[0.9998505,0.00002247914,0.00006144064,0.000008675768,0.00002807878,0.00002883575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004219936,0.0001995294,0.6400242,0.0002522164,0.0002177305,0.0008838623,0.0002852137,0.0002557617,0.3206733,0.00005699152,0.0002176732,0.03271357],"study_design_scores_gemma":[0.00002511467,0.002325851,0.9457014,0.00001615442,0.0001347955,0.001370492,0.0003279865,0.0008070834,0.04822526,0.00007262022,0.0009747078,0.00001852207],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974757,0.001364643,0.0004770867,0.00003517118,0.0000119338,0.00001069471,0.0003612708,0.00001372066,0.0002498346],"genre_scores_gemma":[0.998085,0.0004945993,0.000711877,0.00006456158,0.000008425192,0.00001245678,0.0003122034,0.000002899709,0.0003078777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007259336,"threshold_uncertainty_score":0.001544416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006530517609190229,"score_gpt":0.2256680030346344,"score_spread":0.2191374854254442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}