{"id":"W3107508539","doi":"10.3390/metabo10120487","title":"Untargeted Metabolomics and Polyamine Profiling in Serum before and after Surgery in Colorectal Cancer Patients","year":2020,"lang":"en","type":"article","venue":"Metabolites","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Korea Institute of Science and Technology","keywords":"Metabolomics; Colorectal cancer; Medicine; Putrescine; Arginine; Internal medicine; Cancer; Spermidine; Metabolome; Bioinformatics; Oncology; Gastroenterology; Biochemistry; Chemistry; Biology; Enzyme; Amino acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001117956,0.0001630208,0.000287547,0.00007789187,0.0000246704,0.00001999145,0.00006519487,0.00009037293,0.000007782805],"category_scores_gemma":[0.0001190554,0.0001500439,0.00003561742,0.0002364206,0.00006912951,0.00001175801,0.0001194629,0.00009141838,9.960252e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000445547,"about_ca_system_score_gemma":0.00004034031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008340718,"about_ca_topic_score_gemma":0.0003452819,"domain_scores_codex":[0.9990042,0.00005094226,0.0002590447,0.0003638276,0.00007054138,0.0002514806],"domain_scores_gemma":[0.9997042,0.00001797505,0.00005571963,0.00008671932,0.00003204883,0.0001033848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00007415001,0.00004256976,0.8556082,0.00002238137,0.00001412142,0.000001012341,0.0001236697,0.000001961035,0.1402346,0.0000541258,0.00001326344,0.003809955],"study_design_scores_gemma":[0.0005168369,0.00002171548,0.8123764,0.000005771205,0.00002014802,6.292723e-7,0.0000360693,0.0001173947,0.1841764,0.00004024163,0.002549303,0.0001390854],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868385,0.01220501,0.000009178368,0.0003517512,0.00005122355,0.0002564657,0.0002658516,0.000008022405,0.00001402031],"genre_scores_gemma":[0.9973562,0.001234132,0.0004468797,0.000483055,0.0001267527,0.0001583813,0.0001579733,0.00001956136,0.00001705851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04394184,"threshold_uncertainty_score":0.6118611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006530517609190229,"score_gpt":0.2256680030346344,"score_spread":0.2191374854254442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}