{"id":"W3107805681","doi":"10.5812/gct.110381","title":"The Expression of Wnt5a Gene Throughout Definitive Endoderm Induction Process in Induced Pluripotent Stem Cells","year":2020,"lang":"en","type":"article","venue":"Gene Cell and Tissue","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Endoderm; Homeobox protein NANOG; Ectoderm; Biology; Embryoid body; Wnt signaling pathway; Induced pluripotent stem cell; FOXA2; Cell biology; Mesoderm; WNT5A; Germ layer; Cellular differentiation; Stem cell; Embryonic stem cell; Molecular biology; Embryogenesis; Genetics; Embryo; Gene; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001393221,0.0001893013,0.0001426768,0.000214863,0.00009416771,0.000204535,0.00009749499,0.0001805088,0.0008348349],"category_scores_gemma":[0.0001061586,0.000136161,0.0002454399,0.0001632384,0.0001690456,0.0001222674,0.0001316324,0.0003273982,0.0002464292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002446938,"about_ca_system_score_gemma":0.0002372798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003634177,"about_ca_topic_score_gemma":0.0006070854,"domain_scores_codex":[0.9998221,0.00001667295,0.00002642378,0.00004585444,0.00006790808,0.00002104071],"domain_scores_gemma":[0.9999233,0.00001120065,0.00002596854,0.000009959103,0.00001843174,0.00001100348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002683837,0.000005113739,0.0004478323,0.00004188643,0.000002497098,0.0000529577,0.00001689583,0.00004530714,0.9977469,0.0001289118,0.00002403143,0.00146086],"study_design_scores_gemma":[0.000006598743,0.0001032758,0.007910989,0.00001452252,0.00002105404,0.0002514893,0.00002407391,0.000604117,0.9864085,0.00004865411,0.004603977,0.00000285635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9767536,0.003943314,0.01324979,0.0001068337,0.00005042051,0.0001016463,0.001645758,0.0001036853,0.004044988],"genre_scores_gemma":[0.9805441,0.00205137,0.009242403,0.00007932573,0.000009541095,0.0001134004,0.002377859,0.00002518577,0.005556684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008348349,"threshold_uncertainty_score":0.002792776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02663733832230968,"score_gpt":0.2713767293285118,"score_spread":0.2447393910062021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}