{"id":"W3107805681","doi":"10.5812/gct.110381","title":"The Expression of Wnt5a Gene Throughout Definitive Endoderm Induction Process in Induced Pluripotent Stem Cells","year":2020,"lang":"en","type":"article","venue":"Gene Cell and Tissue","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Endoderm; Homeobox protein NANOG; Ectoderm; Biology; Embryoid body; Wnt signaling pathway; Induced pluripotent stem cell; FOXA2; Cell biology; Mesoderm; WNT5A; Germ layer; Cellular differentiation; Stem cell; Embryonic stem cell; Molecular biology; Embryogenesis; Genetics; Embryo; Gene; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001428839,0.000163052,0.0001765315,0.00003057779,0.0001060247,0.00002339314,0.0002066515,0.0001583378,0.000005828599],"category_scores_gemma":[0.00001487897,0.0001241841,0.00003769206,0.000137357,0.0000767563,0.000007534342,0.0001986398,0.0001605915,0.000009311664],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001419813,"about_ca_system_score_gemma":0.00009084694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003023121,"about_ca_topic_score_gemma":0.00001083737,"domain_scores_codex":[0.9986867,0.0001153405,0.0002716538,0.0004163561,0.000225104,0.000284791],"domain_scores_gemma":[0.9994494,0.00002141181,0.0001147551,0.0002096285,0.00009129216,0.0001134598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001354032,0.00004164001,0.0002617085,0.00007966463,0.00001037023,0.000009103132,0.0005213986,0.0001274489,0.9954136,0.000002724048,0.00007150324,0.003325436],"study_design_scores_gemma":[0.0006443887,0.000325933,0.0002431064,0.00001427406,0.000008157801,0.00000640851,0.000715745,0.00005880555,0.995908,0.00002642055,0.001909909,0.0001389067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956284,0.002971887,0.0002304312,0.0002085684,0.00009050161,0.0003988874,0.00002190111,0.000007147025,0.0004423386],"genre_scores_gemma":[0.9976214,0.001741446,0.000131586,0.00006949648,0.0001327627,0.00003873667,0.00003368161,0.00002167821,0.0002091933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003186529,"threshold_uncertainty_score":0.506408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02663733832230968,"score_gpt":0.2713767293285118,"score_spread":0.2447393910062021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}